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Circadian Rhythm Sleep Disorders clinical trials recruiting in the U.S.
8 studies for Circadian Rhythm Sleep Disorders are recruiting participants at sites across the United States.
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Recently updated studies
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Jul 24, 2026 · NCT06568367Pathophysiology of Circadian Rhythm Delayed Sleep Wake Phase Disorder
RecruitingHealthy volunteers welcome
Ages 16 to 40 · All sexes · Updated Jun 17, 2026 · NCT06471374Pupillometry in Delayed Sleep Wake Phase Disorder
Recruiting
Ages 16 and older · All sexes · Updated Jun 8, 2026 · NCT06949644Lemborexant in Delayed Sleep Phase Syndrome
RecruitingPhase 4Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT06874855Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle
Recruiting
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT05551325Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder
RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated May 11, 2026 · NCT06226025Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated May 4, 2026 · NCT05701969A Pilot of a Personalized Circadian mHealth to Improve Sleep in Night Shift Workers
Recruiting
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06809335From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.