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Amyloidosis clinical trials recruiting in the U.S.
29 studies for Amyloidosis are recruiting participants at sites across the United States.
Amyloidosis is a rare condition that can affect different organs of the body. Find out about amyloidosis treatment and symptoms.
Cities with the most studies
- Boston, MA11 studies
- Rochester, MN10 studies
- New York City, NY10 studies
- Dallas, TX9 studies
- Philadelphia, PA7 studies
- St. Louis, MO6 studies
- Baltimore, MD6 studies
- Houston, TX6 studies
- Durham, NC6 studies
- Portland, OR6 studies
- Washington, DC5 studies
- San Diego, CA5 studies
- Chicago, IL5 studies
- Nashville, TN5 studies
- Cleveland, OH5 studies
- Detroit, MI4 studies
- Charlotte, NC4 studies
- Jacksonville, FL4 studies
- Los Angeles, CA4 studies
- Richmond, VA4 studies
- San Francisco, CA4 studies
- Seattle, WA4 studies
- Edison, NJ3 studies
- Kansas City, KS3 studies
- Austin, TX3 studies
- Columbus, OH3 studies
- Aurora, CO3 studies
- Indianapolis, IN3 studies
- New Haven, CT3 studies
- Kansas City, MO3 studies
- Mountain View, CA3 studies
- Miami, FL3 studies
- Salt Lake City, UT3 studies
- Arlington, VA3 studies
- Atlanta, GA3 studies
- Charleston, SC3 studies
By state
- Arizona3 studies
- California8 studies
- Colorado5 studies
- Connecticut4 studies
- District of Columbia4 studies
- Florida8 studies
- Georgia3 studies
- Illinois5 studies
- Indiana3 studies
- Kansas3 studies
- Maryland7 studies
- Massachusetts11 studies
- Michigan5 studies
- Minnesota10 studies
- Missouri7 studies
- New Jersey3 studies
- New York10 studies
- North Carolina10 studies
- Ohio6 studies
- Oregon6 studies
- Pennsylvania7 studies
- South Carolina4 studies
- Tennessee7 studies
- Texas11 studies
- Utah3 studies
- Virginia4 studies
- Washington4 studies
Recently updated studies
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT07285044A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT05652335Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
RecruitingObservational study
Ages 18 to 130 ยท All sexes ยท Updated Sep 23, 2026 ยท NCT06465810TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
RecruitingPhase 3
Ages 18 to 85 ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07052903TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy
RecruitingPhase 3
Ages 18 to 85 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07223203DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Sep 9, 2026 ยท NCT07358078ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)
RecruitingObservational study
All ages ยท All sexes ยท Updated Sep 8, 2026 ยท NCT04561518Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program
RecruitingObservational study
All ages ยท Women ยท Updated Sep 8, 2026 ยท NCT05040373Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
Recruiting
Ages 65 and older ยท All sexes ยท Updated Sep 1, 2026 ยท NCT05577819Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers
RecruitingObservational study
Ages 30 to 80 ยท All sexes ยท Updated Aug 31, 2026 ยท NCT05489549Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Aug 19, 2026 ยท NCT05145816Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Aug 4, 2026 ยท NCT06563895Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis
RecruitingPhase 4
Ages 18 to 80 ยท All sexes ยท Updated Jul 29, 2026 ยท NCT07695701A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis
RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Jul 24, 2026 ยท NCT05951816[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Jul 21, 2026 ยท NCT07560306A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Cyclophosphamide, Bortezomib, and Dexamethasone in Adult Participants With Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Jul 17, 2026 ยท NCT07224672A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Jul 2, 2026 ยท NCT07081646Dietary Reporting In The Amyloidoses
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jun 26, 2026 ยท NCT05738005Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load
RecruitingPhase 1
Ages 18 to 120 ยท All sexes ยท Updated May 19, 2026 ยท NCT06974877A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated May 13, 2026 ยท NCT06158854Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis
RecruitingPhase 2
Ages 40 to 90 ยท All sexes ยท Updated Apr 13, 2026 ยท NCT05758493MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
RecruitingPhase 3
Ages 18 to 90 ยท All sexes ยท Updated Mar 27, 2026 ยท NCT06128629Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study
RecruitingObservational study
Ages 30 to 80 ยท All sexes ยท Updated Jan 7, 2026 ยท NCT07196839Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Dec 31, 2025 ยท NCT04991103A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography
RecruitingObservational study
Ages 20 and older ยท All sexes ยท Updated Dec 26, 2025 ยท NCT07216469From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.