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Angelman Syndrome clinical trials recruiting in the U.S.
5 studies for Angelman Syndrome are recruiting participants at sites across the United States.
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Recently updated studies
CHAMPION: A Study to Evaluate the Efficacy and Safety of Obudanersen (ION582) in Children and Adults With Angelman Syndrome (AS)
RecruitingPhase 3
Ages 2 to 50 · All sexes · Updated Sep 28, 2026 · NCT07782827BEACON - Phase III Clinical Study of Rugonersen in Angelman Syndrome.
RecruitingPhase 3
Ages 1 to 50 · All sexes · Updated Sep 10, 2026 · NCT07605429A Natural History Study of Angelman Syndrome
RecruitingObservational study
Ages 1 and older · All sexes · Updated Aug 21, 2026 · NCT07417137A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome
RecruitingPhase 1/2
Ages 4 to 50 · All sexes · Updated Jul 24, 2026 · NCT07181837Angelman Syndrome Natural History Study
RecruitingObservational study
All ages · All sexes · Updated Apr 3, 2025 · NCT04507997From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.