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Arrhythmia clinical trials recruiting in the U.S.
40 studies for Arrhythmia are recruiting participants at sites across the United States.
Arrhythmia, also called irregular heartbeat comes in different types. The most common is atrial fibrillation. Read about symptoms and treatment.
Cities with the most studies
- New York City, NY8 studies
- Rochester, MN7 studies
- San Francisco, CA5 studies
- Mountain View, CA5 studies
- Austin, TX5 studies
- Cleveland, OH5 studies
- Philadelphia, PA5 studies
- Boston, MA4 studies
- Santa Clarita, CA4 studies
- Washington, DC4 studies
- Houston, TX4 studies
- Durham, NC3 studies
- Chicago, IL3 studies
- Detroit, MI3 studies
- Jacksonville, FL3 studies
- Pittsburgh, PA3 studies
- Nashville, TN3 studies
- Louisville, KY3 studies
- Indianapolis, IN3 studies
- Madison, WI3 studies
- San Diego, CA3 studies
- St. Louis, MO3 studies
By state
- Arizona4 studies
- California17 studies
- District of Columbia3 studies
- Florida5 studies
- Georgia3 studies
- Illinois3 studies
- Indiana3 studies
- Kentucky4 studies
- Maryland4 studies
- Massachusetts4 studies
- Michigan5 studies
- Minnesota7 studies
- Missouri5 studies
- New Jersey3 studies
- New York10 studies
- North Carolina9 studies
- Ohio7 studies
- Pennsylvania6 studies
- South Carolina3 studies
- Tennessee4 studies
- Texas9 studies
- Utah4 studies
- Virginia5 studies
- Washington3 studies
- Wisconsin4 studies
Recently updated studies
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07217067BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
Recruiting
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07118358Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 18, 2026 · NCT07585968Feasibility and Usability of a Chest-Strap Ambulatory ECG Monitor in Active Individuals in Comparison With a Traditional Ambulatory ECG Patch Monitor (MoMe ARC)
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 17, 2026 · NCT07772817Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT00921986Early Screening and Treatment of Heart Complication in Sickle Cell Disease
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07023666Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 8, 2026 · NCT07122947Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation
Recruiting
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06938412Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404NOrthwestern Tempus AI-enaBLed Electrocardiography (NOTABLE) Trial
RecruitingHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Aug 20, 2026 · NCT06511505Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax
RecruitingObservational study
Ages 18 to 110 · All sexes · Updated Aug 7, 2026 · NCT05724121Evaluation of A Clinical Diagnostic Test for CRDS
Recruiting
All ages · All sexes · Updated Jul 22, 2026 · NCT06188689Safety and Efficacy of the Sentinel Cerebral Protection Device in Atrial Fibrillation Ablation
Recruiting
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT04685317A Usability Study of a Multi-channel ECG Monitoring Device
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT07388355HeartBeam ECG Registry
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 20, 2026 · NCT07501299The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT05034432A Phase 2 Study of CRD-4730 in CPVT
RecruitingPhase 2
Ages 18 to 99 · All sexes · Updated Jul 9, 2026 · NCT06658899ViewFlex X ICE First-in-Human Study
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06772493AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT06699056Aveir DR Real-World Evidence Post-Approval Study
RecruitingObservational study
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT05935007Tulane iPredict, Prevent Study to Evaluate the Progression of Atrial Myopathy.
RecruitingObservational study
Ages 18 to 79 · All sexes · Updated May 19, 2026 · NCT04703166Developing a Digital Aid to Improve ICD Decisions
Recruiting
Ages 60 and older · All sexes · Updated Apr 27, 2026 · NCT07084142Mayo AVC Registry and Biobank
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 27, 2026 · NCT03049254From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.