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Autoimmune Diseases clinical trials recruiting in the U.S.
77 studies for Autoimmune Diseases are recruiting participants at sites across the United States.
Autoimmune diseases are where your immune system attacks healthy cells in your body by mistake. Learn about the symptoms, tests, and treatments.
Cities with the most studies
- Houston, TX21 studies
- Washington, DC19 studies
- New York City, NY19 studies
- Philadelphia, PA17 studies
- Durham, NC15 studies
- Boston, MA13 studies
- Chicago, IL13 studies
- Los Angeles, CA12 studies
- Atlanta, GA9 studies
- Dallas, TX9 studies
- Miami, FL8 studies
- Milwaukee, WI8 studies
- Cleveland, OH8 studies
- Portland, OR8 studies
- San Francisco, CA7 studies
- Orange, CA7 studies
- Seattle, WA7 studies
- Pittsburgh, PA7 studies
- Cedar Rapids, IA7 studies
- Memphis, TN6 studies
- Salt Lake City, UT6 studies
- Rochester, MN6 studies
- Louisville, KY6 studies
- Kansas City, KS6 studies
- Baltimore, MD6 studies
- Ann Arbor, MI6 studies
- Jacksonville, FL6 studies
- The Bronx, NY6 studies
- New Haven, CT5 studies
- Phoenix, AZ5 studies
- Mountain View, CA5 studies
- Orlando, FL5 studies
- Nashville, TN5 studies
- Sacramento, CA5 studies
- Aurora, CO5 studies
- San Diego, CA5 studies
- Oklahoma City, OK4 studies
- Charleston, SC4 studies
- Tampa, FL4 studies
- Denver, CO4 studies
By state
- Alabama5 studies
- Arizona7 studies
- Arkansas4 studies
- California28 studies
- Colorado9 studies
- Connecticut5 studies
- District of Columbia6 studies
- Florida22 studies
- Georgia11 studies
- Illinois17 studies
- Indiana4 studies
- Iowa7 studies
- Kansas7 studies
- Kentucky8 studies
- Maryland21 studies
- Massachusetts15 studies
- Michigan9 studies
- Minnesota9 studies
- Missouri7 studies
- Nebraska3 studies
- New Jersey5 studies
- New York24 studies
- North Carolina20 studies
- Ohio13 studies
- Oklahoma4 studies
- Oregon9 studies
- Pennsylvania22 studies
- South Carolina4 studies
- Tennessee10 studies
- Texas24 studies
- Utah7 studies
- Virginia7 studies
- Washington8 studies
- Wisconsin8 studies
Recently updated studies
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Nov 13, 2026 · NCT07039916RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
RecruitingPhase 2/3
Ages 6 to 75 · All sexes · Updated Nov 13, 2026 · NCT06154252Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathy
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07103746Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity
RecruitingPhase 2
Ages 4 to 69 · All sexes · Updated Nov 12, 2026 · NCT04339777Study of Autoimmune Lymphoproliferative Syndrome (ALPS)
RecruitingObservational study
Up to age 99 · All sexes · Updated Nov 12, 2026 · NCT00001350Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04751396Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03816345Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death
RecruitingObservational study
1 Month – 100 Years · All sexes · Updated Nov 12, 2026 · NCT00246857Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT00867269A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Nov 12, 2026 · NCT06056297Natural History of Bronchiectasis
RecruitingObservational studyHealthy volunteers welcome
Ages 5 to 100 · All sexes · Updated Nov 12, 2026 · NCT00943514Secukinumab Open Label Roll-over Extension Protocol
RecruitingPhase 4
Ages 6 to 100 · All sexes · Updated Nov 9, 2026 · NCT04638647Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Nov 9, 2026 · NCT04097561Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07621809Study of PTC844 in Participants With Active Rheumatoid Arthritis
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Nov 6, 2026 · NCT07779616Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
RecruitingPhase 2Healthy volunteers welcome
Ages 4 to 75 · All sexes · Updated Nov 5, 2026 · NCT02579967A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06722235A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A Nephropathy
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07902817Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06434363A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
RecruitingPhase 1
Ages 18 to 74 · All sexes · Updated Nov 2, 2026 · NCT07085104NIAID Centralized Sequencing Protocol
RecruitingObservational studyHealthy volunteers welcome
1 Day – 100 Years · All sexes · Updated Nov 2, 2026 · NCT03206099A Study of JADE101 in Participants With Immunoglobulin A Nephropathy
RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated Oct 30, 2026 · NCT07541287A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06948318Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
RecruitingPhase 2
Ages 18 to 90 · All sexes · Updated Oct 26, 2026 · NCT00977977Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye Disease
RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT07885605From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.