Home › Bone Cancer
Bone Cancer clinical trials recruiting in the U.S.
20 studies for Bone Cancer are recruiting participants at sites across the United States.
Bone cancer comes in three types: Osteosarcoma, Chondrosarcoma, and Ewing's sarcoma. Learn how bone cancer is diagnosed and treated.
Cities with the most studies
By state
Recently updated studies
Intraoperative Neuromonitoring of Sacral Reflexes to Predict Post Operative Function in Patients Undergoing Sacrectomy for Pelvic Bone Malignancy or Patients Undergoing Spinal Procedures Without Sacral Root Involvement
Recruiting
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07707024Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
RecruitingPhase 1
Ages 12 to 50 · All sexes · Updated Nov 10, 2026 · NCT03093909Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Nov 5, 2026 · NCT03160274Iscador® P (Mistletoe) Immunotherapy for Recurrent Resectable Osteogenic Sarcoma
RecruitingPhase 2
Ages 8 to 30 · All sexes · Updated Nov 4, 2026 · NCT05726383XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06571734A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07193550Financial Toxicity in Patients With Resected Soft Tissue and Bone Sarcomas
RecruitingObservational study
All ages · All sexes · Updated Sep 11, 2026 · NCT07215611Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention
Recruiting
Ages 15 to 39 · All sexes · Updated Aug 26, 2026 · NCT07662239Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma
Recruiting
All ages · All sexes · Updated Aug 21, 2026 · NCT07514819Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT03965234Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT06409013U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures
Recruiting
Ages 22 and older · All sexes · Updated Jul 20, 2026 · NCT07325578Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT05419518Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma
Recruiting
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT06129903Samarium Optimized for Long-lasting Analgesia in Cancerous End-stage Bone Pain
RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT07197645Mg OSTEOCRETE Post-Treatment Outcomes
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT06720142Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas
RecruitingObservational study
Ages 4 and older · All sexes · Updated Apr 17, 2026 · NCT03442465Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone
RecruitingObservational study
Ages 15 and older · All sexes · Updated Mar 13, 2026 · NCT05033288An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor Registry
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 11, 2026 · NCT02677961Definitive Radiation for High-Risk Spine Metastases
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 14, 2025 · NCT06165419From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.