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Breast Cancer clinical trials in Kentucky
24 studies for Breast Cancer are looking for participants at sites in Kentucky.
Cities in Kentucky
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
- Baptist Health Lexington ( Site 0050), Lexington
- Baptist Health Hamburg ( Site 0071), Lexington
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07060807A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
- Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 0053), Edgewood
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312176A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
- University of Kentucky Chandler Medical Center, Lexington
RecruitingPhase 2
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07287098A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
- Saint Elizabeth Medical Center Edgewood, Edgewood
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
- University Medical Center, Inc. DBA University of Louisville Hospital/James Graham Brown Cancer Center, Louisville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
- UofL Health Brown Cancer Center, Louisville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer
- Research Site, Edgewood
- Research Site, Louisville
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 8, 2026 · NCT07647328Toci +/- SOC Chemo for Metastatic Triple Negative and ER-positive, HER2-negative Breast Cancers
- University of Kentucky-Lexington, Lexington
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT05846789A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
- Baptist Health Lexington, Lexington
- Baptist Health Hamburg, Lexington
- University of Kentucky - Markey Cancer Center, Lexington
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06790693Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- CommonSpirit Saint Joseph Hospital - Bardstown, Bardstown
- Commonwealth Cancer Center-Corbin, Corbin
- Saint Elizabeth Healthcare Edgewood, Edgewood
- and 5 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
- King's Daughter's Medical Center, Ashland
- CommonSpirit Saint Joseph Hospital - Bardstown, Bardstown
- Baptist Health Corbin, Corbin
- and 13 more
RecruitingPhase 3
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926A Phase 1 Study of LNCB74 in Advanced Solid Tumors
- St. Elizabeth Healthcare, Edgewood
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06774963E-Mindfulness Approaches for Living After Breast Cancer
- King's Daughter's Medical Center, Ashland
- CommonSpirit Saint Joseph Hospital - Bardstown, Bardstown
- CommonSpirit Saint Joseph Medical Center - East Lexington, Lexington
- and 1 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222EXoPERT EMERALD Clinical Study
- Lexington VA Healthcare System, Lexington
- KCTL, Louisville
RecruitingObservational studyHealthy volunteers welcome
Ages 45 and older · All sexes · Updated Jul 1, 2026 · NCT07186296Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
- Norton Cancer Institute, Louisville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT05696626Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
- UK Markey Cancer Center, Lexington
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
- Mercy Health-Paducah Cancer Center, Paducah
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06757634De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
- Saint Joseph Hospital, Lexington
- Saint Joseph Radiation Oncology Resource Center, Lexington
- Saint Joseph Hospital East, Lexington
- and 1 more
RecruitingPhase 3
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
- Flaget Memorial Hospital, Bardstown
- Saint Joseph Hospital East, Lexington
- Saint Joseph London, London
- and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
- University of Kentucky Markey Cancer Center, Lexington
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- Baptist Corbin, Corbin
- Baptist Hardin, Elizabethtown
- Baptist Lexington, Lexington
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
- St. Elizabeth Edgewood Hospital, Edgewood
- Norton Cancer Institute - Downtown, Louisville
- Baptist Health Louisville, Louisville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06401421S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
- Saint Joseph Hospital East, Lexington
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961Study of Palliative Radiation Combined with Pembrolizumab in Unresectable Metastatic Stage IV Breast Cancer
- James Graham Brown Cancer Center, Louisville
RecruitingPhase 2
Ages 18 and older · Women · Updated Feb 20, 2025 · NCT04990921From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.