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Breast Cancer clinical trials in Wisconsin

44 studies for Breast Cancer are looking for participants at sites in Wisconsin.

Cities in Wisconsin

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

  • University of Wisconsin-Madison ( Site 0024), Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06966700

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Zablocki Veterans Administration Medical Center, Milwaukee
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Nov 6, 2026 · NCT06995898

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

  • University of Wisconsin, Madison
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07214532

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

  • University of Wisconsin Carbone Cancer Center- University Hospital, Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06982521

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

  • ThedaCare Physicians - Appleton North, Appleton
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07174336

E-Mindfulness Approaches for Living After Breast Cancer

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • ThedaCare Cancer Care - Berlin, Berlin
  • and 38 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Nov 4, 2026 · NCT06748222

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • ThedaCare Regional Medical Center - Appleton, Appleton
  • and 50 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Aspirus Langlade Hospital, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • Ascension Saint Elizabeth Hospital, Appleton
  • and 61 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06418204

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

  • University of Wisconsin - Carbone Cancer Center, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07213791

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • Duluth Clinic Ashland, Ashland
  • and 63 more
RecruitingPhase 3
Ages 18 to 60 · Women · Updated Nov 4, 2026 · NCT05879926

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

  • Circuit Clinical/SSM Health Dean Medical Group ( Site 0039), Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07060807

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

  • Medical College of Wisconsin, Milwaukee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07173751

Individuals on Hormone Therapy Breast Cancer Screening Pilot

  • Medical College of Wisconsin, Milwaukee
RecruitingObservational studyHealthy volunteers welcome
Ages 30 to 75 · All sexes · Updated Oct 30, 2026 · NCT06383026

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

  • University of Wisconsin, Madison
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07102381

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • Froedtert & MCW Cancer Center, Milwaukee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07109726

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

  • Froedtert Hospital - MCW Clinical Trials Office, Milwaukee
  • Aurora Cancer Care - Wauwatosa, Wauwatosa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT06401421

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

  • University of Wisconsin-Madison Carbone Cancer Center, Madison
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT07287917

Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

  • Froedtert Hospital and the Medical College of Wisconsin, Milwaukee
RecruitingPhase 2
Ages 18 and older · Women · Updated Oct 20, 2026 · NCT06361940

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT06582017

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

  • Aurora BayCare Medical Center, Green Bay
  • Aurora St Luke's Medical Center, Milwaukee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT07062965

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

  • University Hospital and UW Health Clinics-Carbone Cancer Center ( Site 0040), Madison
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06312176

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of Wisconsin Carbone Cancer Center, Madison
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

  • Wisconsin Institute for Medical Research, Madison
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

  • Research Site, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

  • Clinical Trial Site, Milwaukee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

  • University of Wisconsin, Madison
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT04886531

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

  • Gunderson Health, La Crosse
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07211178

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

  • Sheboygan Cancer & Blood Specialists, Sheboygan
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

Study of 18F-FFNP Breast PET/MRI

  • UW Carbone Cancer Center, Madison
RecruitingPhase 2
Ages 18 and older · Women · Updated Aug 31, 2026 · NCT06086704

Biomarkers to Detect Endocrine Therapy Resistance

  • UW Carbone Cancer Center, Madison
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06067503

Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial

  • Froedtert Hospital, Milwaukee
Recruiting
Ages 65 and older · All sexes · Updated Aug 20, 2026 · NCT07227077

Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer

  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06106477

Integrated Cancer Repository for Cancer Research

  • Bellin Memorial Hospital, Green Bay
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

  • University of Wisconsin Carbone Cancer Center, Madison
RecruitingPhase 2
Ages 40 and older · Women · Updated Jun 11, 2026 · NCT03936478

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

  • Langlade Hospital and Cancer Center, Antigo
  • Aurora Cancer Care-Southern Lakes VLCC, Burlington
  • Marshfield Medical Center-EC Cancer Center, Eau Claire
  • and 43 more
RecruitingPhase 3
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

  • Medical College of Wisconsin, Milwaukee
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer

  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT02926690

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.