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Cancer (all types) clinical trials in Ohio
87 studies for Cancer (all types) are looking for participants at sites in Ohio.
Cities in Ohio
- Columbus39 studies
- Cleveland37 studies
- Cincinnati28 studies
- Akron14 studies
- Dayton8 studies
- Toledo7 studies
- Parma4 studies
- Mentor3 studies
A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
- Investigative Site, Canton
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06881992Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
- UHHS-Chagrin Highlands Medical Center, Beachwood
- Aultman Health Foundation, Canton
- Miami Valley Hospital South, Centerville
- and 13 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Sep 28, 2026 · NCT05256225Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
- The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Dayton Physician's Network, Dayton
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
- The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0008), Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06979596Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
- The Ohio State University, Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07195591A Tailored Medication Adherence-Promotion Intervention for Adolescents and Young Adults With Cancer
- Cincinnati Children's Hospital Medical Center, Cincinnati
Recruiting
Ages 15 to 24 · All sexes · Updated Sep 24, 2026 · NCT07223463A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
- Oncology Hematology Care - Fairfield /ID# 280641, Fairfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
- Quetzal Site 8, Columbus
RecruitingPhase 3
Ages 18 to 71 · All sexes · Updated Sep 23, 2026 · NCT07504458Pan Tumor Rollover Study
- Oncology Hematology Care, Cincinnati
- The Ohio University, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03899155TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- University of Cincinnati Medical Center, Cincinnati
- Kettering Health, Kettering
- West Chester Hospital, West Chester
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Visugromab in Cachexia International Trial
- Cleveland Clinic Avon Hospital, Avon
- Cleveland Clinic (Main Campus), Cleveland
- Cleveland Clinic Fairview Hospital, Fairview
- and 1 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07112196Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- Oncology Hematology Care, Inc., Cincinnati
- University Hospitals of Cleveland, Cleveland
- Cleveland Clinic Foundation, Cleveland
- and 1 more
RecruitingPhase 2/3
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796Collection of Tissue Samples for Cancer Research
- Ohio State University, Columbus
RecruitingObservational study
2 Months · All sexes · Updated Sep 16, 2026 · NCT00900198Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance
- University Hospitals Cleveland Medical Center, Cleveland
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05796375Statins to Prevent Cancer Associated Blood Clots
- Cleveland Clinic Foundation, Cleveland
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07303816A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
- GSK Investigational Site, Canton
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07213609Met Non Small Cell Cancer Registry (MOMENT)
- The Ohio State University Wexner Medical Center, Columbus
RecruitingObservational study
All ages · All sexes · Updated Sep 15, 2026 · NCT05376891RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Cleveland Clinic, Cleveland
- The Ohio State University, Department of Psychiatry, Columbus
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
- Oncology Hematology Care Clinical Trials, LLC, Fairfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07566156Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
- Miami Valley Hospital South, Centerville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05386108A Phase 1/1b Study of IAM1363 in HER2 Cancers
- University Hospital Cleveland Medical Center, Cleveland
- Cleveland Clinic, Cleveland
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- Miami Valley Hospital South, Centerville
- USO - Oncology Hematology Care, Cincinnati
- The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T, Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
- University of Cincinnati, Cincinnati
- Cleveland Clinic, Cleveland
- Ohio State University, Columbus
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
- Gabrail Cancer & Research Center, Canton
- Cleveland Clinic, Cleveland
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612Project: Every Child for Younger Patients With Cancer
- Children's Hospital Medical Center of Akron, Akron
- Cincinnati Children's Hospital Medical Center, Cincinnati
- Rainbow Babies and Childrens Hospital, Cleveland
- and 5 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma
- University Hospitals Cleveland Medical Center, Cleveland
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT07192471Abatacept in Immune Checkpoint Inhibitor Myocarditis
- Cleveland Clinic, Cleveland
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05335928A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
- Cleveland Clinic, Cleveland
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Aug 20, 2026 · NCT06678659FOG-001 in Locally Advanced or Metastatic Solid Tumors
- University Hospitals Cleveland Medical Center, Seidman Cancer Center, Cleveland
- Cleveland Clinic, Cleveland
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
- The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- OhioHealth O'Bleness Hospital, Athens
- UHHS-Chagrin Highlands Medical Center, Beachwood
- Geauga Hospital, Chardon
- and 26 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314International Rare Brain Tumor Registry
- Akron Children's Hospital, Akron
- Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingObservational study
Up to age 45 · All sexes · Updated Aug 7, 2026 · NCT05697874A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
- Nationwide Children's Hosp, Columbus
RecruitingPhase 2
Ages 1 to 39 · All sexes · Updated Aug 7, 2026 · NCT05999994Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
- University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
- Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center, Cleveland
RecruitingPhase 2
Ages 19 and older · All sexes · Updated Aug 6, 2026 · NCT06129747Feasibility and Acceptability of Wearable Sensors and ePROs in Early Phase Clinical Trials
- Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT07541365Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
- Nationwide Children's Hospital, Columbus
RecruitingPhase 2
Ages 1 to 26 · All sexes · Updated Aug 4, 2026 · NCT07680439A Study of ASP3082 in Adults With Advanced Solid Tumors
- Case Western, Cleveland
- Taylor Cancer Research Center, Maumee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT05382559Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
- University of Cincinnati Physicians Group, LLC, Cincinnati
RecruitingPhase 3
Ages 18 and older · Women · Updated Jul 28, 2026 · NCT07022483A Study of ASP1002 in Adults for Treatment of Solid Tumors
- University Hospitals of Cleveland, Cleveland
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT05719558From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.