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Cancer (all types) clinical trials in Tennessee

91 studies for Cancer (all types) are looking for participants at sites in Tennessee.

Cities in Tennessee

Bexmarilimab + Azacitidine Versus Placebo + Azacitidine in Participants With Treatment-naïve Higher-risk Myelodysplastic Syndromes

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07672769

Post-Marketing Study for Early-Stage Low-Risk Breast Cancer Treatment Using ProSense® Cryoablation (ChoICE Trial)

  • The West Clinic, PC dba West Cancer Center, Germantown
Recruiting
Ages 70 and older · All sexes · Updated Nov 12, 2026 · NCT07629206

A Study of YL242 in Subjects With Advanced Solid Tumors

  • US-205, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07197827

Childhood Cancer Predisposition Study (CCPS)

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational study
All ages · All sexes · Updated Nov 12, 2026 · NCT04511806

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

  • Vanderbilt Ingram Cancer Center /ID# 252470, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT05650632

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

  • Alliance for Multispecialty Research Clinical, Knoxville
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 10, 2026 · NCT07002034

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

  • Vanderbilt-Ingram Cancer Center at Franklin, Franklin
  • Vanderbilt-Ingram Cancer Center Cool Springs, Franklin
  • Vanderbilt Breast Center at One Hundred Oaks, Nashville
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT06580314

Pan Tumor Rollover Study

  • Tennesse Oncology, Nashville
  • Local Institution - 0066, Nashville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT03899155

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

  • University of Tennessee Health Science Center, Knoxville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT04198766

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

  • SCRI Oncology Partners - PPDS, Nashville
RecruitingPhase 1
Ages 18 to 99 · All sexes · Updated Nov 5, 2026 · NCT07540572

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

  • The University of Tennessee Medical Center, Knoxville
  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06901531

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

  • Sarah Cannon Cancer Institute, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06150157

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • Tennessee Oncology Chattanooga, Chattanooga
  • University of Tennessee Medical Center, Knoxville
  • Baptist Memorial Hospital-Memphis, Memphis
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06119581

A Study of JNJ-87890387 for Advanced Solid Tumors

  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06178614

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

  • Sarah Cannon Research Inst, Nashville
RecruitingPhase 2/3
All ages · All sexes · Updated Nov 2, 2026 · NCT03435796

Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

  • Sarah Cannon Research Institute at TriStar Centennial Medical Center, Nashville
RecruitingPhase 3
Ages 18 to 71 · All sexes · Updated Oct 30, 2026 · NCT07504458

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

  • SCRI Oncology Partners, Nashville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07566156

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

  • Research Site, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06835569

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

  • Vanderbilt University Medical Center, Nashville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT04981119

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

  • St. Jude Children's Research Hospital, Memphis
RecruitingPhase 2
Ages 2 to 99 · All sexes · Updated Oct 21, 2026 · NCT05783323

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

  • SCRI Oncology Partners ( Site 7000), Nashville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT07405164

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

  • Research Site, Nashville
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 19, 2026 · NCT07647328

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

  • Baptist Medical Center, Memphis
  • Tennessee Oncology, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT06162221

Galleri® in the Medicare Population.

  • HCA Healthcare Brentwood, Brentwood
  • HCA Healthcare Centennial, Nashville
  • HCA Healthcare Nashville, Nashville
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Oct 19, 2026 · NCT05673018

Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures

  • Vanderbilt University Medical Center, Nashville
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07493447

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

  • Henry-Joyce Cancer Clinic, Nashville
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06989437

A Study of ASP3082 in Adults With Advanced Solid Tumors

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT05382559

Suprachoroidal Administration in Subjects With Metastases to the Choroid

  • Tennessee Retina, PC, Nashville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT06643884

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • Sarah Cannon Research Institute, Nashville
  • Vanderbilt Ingram Cancer Center, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 7, 2026 · NCT05919264

A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

  • Tennessee Cancer Specialists - Knoxville - Old Weisgarber Road /ID# 277891, Knoxville
  • SCRI Oncology Partners /ID# 276959, Nashville
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07155187

A Study of PHN-012 in Patients With Advanced Solid Tumors

  • PHN-012-001 Site, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

  • Vanderbilt University Medical Center, Nashville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05874921

Registry Study for Radiation Therapy Outcomes

  • Tennessee Oncology Proton Center, Franklin
  • Thompson Proton Center, Knoxville
RecruitingObservational study
All ages · All sexes · Updated Sep 29, 2026 · NCT01255748

A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors

  • SCRI Oncology Partners, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07612176

A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

  • GSK Investigational Site, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07277270

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

  • Tennessee Cancer Specialists - Knoxville - Old Weisgarber Road /ID# 280619, Knoxville
  • University Of Tennessee Medical Center /ID# 279896, Knoxville
  • Baptist Memorial Hospital /ID# 281405, Memphis
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

  • Tennessee Oncology - Nashville / Sarah Cannon Research Institute, Nashville
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.