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Chronic Kidney Disease clinical trials recruiting in the U.S.

114 studies for Chronic Kidney Disease are recruiting participants at sites across the United States.

If your kidneys are damaged and can't filter blood easily, then you may suffer from chronic kidney disease (CKD). Read about the treatments available

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Recently updated studies

Immune System Related Kidney Disease

RecruitingObservational study
Ages 10 to 99 · All sexes · Updated Nov 12, 2026 · NCT00001979

Ticagrelor for Inflammation and Cardiovascular Risk in Patients With Chronic Kidney Disease

RecruitingPhase 2Healthy volunteers welcome
Ages 21 to 75 · All sexes · Updated Nov 10, 2026 · NCT07911124

University of Michigan "Nephrology Research BioBank"

RecruitingObservational study
All ages · All sexes · Updated Nov 10, 2026 · NCT00381121

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Nov 10, 2026 · NCT07235059

Effects of Replacing High Protein Foods in People With Chronic Kidney Disease

Recruiting
Ages 40 to 70 · All sexes · Updated Nov 9, 2026 · NCT07105670

A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07268638

Transcutaneous Auricular Vagus Nerve Stimulation Device in CKD Population

Recruiting
Ages 18 to 80 · All sexes · Updated Nov 5, 2026 · NCT05981183

Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes

Recruiting
Ages 30 to 75 · All sexes · Updated Nov 4, 2026 · NCT07868666

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07783802

Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD

RecruitingPhase 2
Ages 40 to 75 · All sexes · Updated Oct 30, 2026 · NCT05928936

Diuretic Tuner Clinical Decision Support

Recruiting
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT04759274

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)

Recruiting
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06927024

Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease

RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Oct 27, 2026 · NCT07271186

A Natural History Study of Metabolic Sizing in Health and Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 99 · All sexes · Updated Oct 27, 2026 · NCT05398783

Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias

RecruitingObservational study
Ages 19 and older · All sexes · Updated Oct 26, 2026 · NCT06306963

The KidneyCARE (Community Access to Research Equity) Study

RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 26, 2026 · NCT05497518

SPYRAL GEMINI Pilot Study

Recruiting
Ages 18 to 80 · All sexes · Updated Oct 20, 2026 · NCT06907147

Addition of Venetoclax to Combined Hematopoietic Stem Cell and Kidney Transplantation

RecruitingEarly phase 1
Ages 18 to 70 · All sexes · Updated Oct 14, 2026 · NCT07358195

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

RecruitingObservational study
Ages 21 to 80 · All sexes · Updated Oct 13, 2026 · NCT04185844

A Study of Luspatercept in People With Anemia

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07725497

CKD Awareness, Referrals, Education, and Support Intervention for Early-Stage CKD

Recruiting
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT07210710

Physical Activity in CKD

Recruiting
Ages 13 to 18 · All sexes · Updated Oct 8, 2026 · NCT06624358

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.