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Cocaine clinical trials recruiting in the U.S.

5 studies for Cocaine are recruiting participants at sites across the United States.

Cocaine, also called crack cocaine, is a highly addictive stimulant. It can be snorted, injected, or smoked. Learn about health effects and treatment.

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Recently updated studies

Safety Study of a Disrupted Adenovirus (Ad) Serotype Cocaine Vaccine for Cocaine-dependent Individuals

RecruitingPhase 1
Ages 21 to 69 · All sexes · Updated Aug 26, 2026 · NCT02455479

rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder

Recruiting
Ages 22 to 65 · All sexes · Updated Aug 17, 2026 · NCT05974202

Repurposing Semaglutide for the Treatment of Cocaine Use Disorder

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 19, 2026 · NCT07227948

Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder

Recruiting
Ages 18 to 60 · All sexes · Updated Mar 3, 2026 · NCT07318480

Smartphone Services for Stimulant Use Disorder

Recruiting
Ages 18 and older · All sexes · Updated Jul 29, 2025 · NCT07092059

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.