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Complex Regional Pain Syndrome clinical trials recruiting in the U.S.

12 studies for Complex Regional Pain Syndrome are recruiting participants at sites across the United States.

Complex regional pain syndrome, CRPS or Reflex Sympathetic Dystrophy, RSD are chronic pain conditions. They cause intense pain and can spread.

Cities with the most studies

By state

Recently updated studies

CRPS-RISE Outcomes Registry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07811362

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07210515

Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients

Recruiting
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07791966

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Recruiting
Ages 22 to 80 · All sexes · Updated Jul 31, 2026 · NCT04144972

TMS for Complex Regional Pain Syndrome

Recruiting
Ages 18 to 70 · All sexes · Updated Jun 23, 2026 · NCT03137472

Supraspinal Processing of Sensory Aspects of Pain

RecruitingHealthy volunteers welcome
Ages 10 to 17 · All sexes · Updated Jun 5, 2026 · NCT05814497

Infrared Images for Spinal Cord Stimulation in Complex Regional Pain Syndrome Patients

RecruitingObservational study
Ages 18 to 85 · All sexes · Updated Nov 26, 2025 · NCT05777889

Role of the Gut Microbiome in Complex Regional Pain Syndrome

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 5, 2025 · NCT03612193

Closed Loop Spinal Cord Stimulation for Complex Regional Pain Syndrome

Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2025 · NCT06421350

Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome

Recruiting
Ages 18 to 70 · All sexes · Updated May 29, 2025 · NCT02502162

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.