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Coronary Artery Disease clinical trials recruiting in the U.S.

66 studies for Coronary Artery Disease are recruiting participants at sites across the United States.

Coronary artery disease (CAD) is the most common type of heart disease. It can lead to angina and heart attack. Read about symptoms and tests.

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Recently updated studies

The NAVIGATE-PCI Registry: A New Approach to VIew CT-derived Guidance Ahead of Stenting To Plan Efficient PCI

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07479433

A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease

RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Nov 10, 2026 · NCT07839936

PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

Recruiting
Ages 18 to 90 · All sexes · Updated Nov 9, 2026 · NCT06445608

The Bridging Antiplatelet Therapy With Cangrelor 2 Study

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07225842

A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 5, 2026 · NCT07521007

Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma

Recruiting
Ages 55 and older · All sexes · Updated Nov 2, 2026 · NCT07704918

Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

Recruiting
Ages 18 to 90 · All sexes · Updated Nov 2, 2026 · NCT07296744

Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors

RecruitingObservational study
Ages 18 to 99 · Men · Updated Oct 30, 2026 · NCT05611307

Lifewise Preventive Video Education in Primary Care

RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Oct 29, 2026 · NCT06730737

Virtue® SAB in the Treatment of Coronary ISR Trial

Recruiting
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT07045194

Prevail Global Study

Recruiting
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT06535854

Product Surveillance Registry

RecruitingObservational study
All ages · All sexes · Updated Oct 20, 2026 · NCT01524276

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

Recruiting
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT05427370

Prevent Cardiac Surgery Associated AKI Trial

RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Oct 14, 2026 · NCT06620523

ASCVD Management Using CCTA in Prostate Cancer Patients on ADT

Recruiting
Ages 40 and older · Men · Updated Oct 5, 2026 · NCT05879913

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07559903

IVUS CHIP UPP Registry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06625801

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.