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Coronary Artery Disease clinical trials recruiting in the U.S.

68 studies for Coronary Artery Disease are recruiting participants at sites across the United States.

Coronary artery disease (CAD) is the most common type of heart disease. It can lead to angina and heart attack. Read about symptoms and tests.

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Recently updated studies

CTSN Embolic Protection Trial

Recruiting
Ages 60 and older · All sexes · Updated Sep 28, 2026 · NCT06027788

IVUS CHIP UPP Registry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06625801

Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

Recruiting
Ages 18 to 90 · All sexes · Updated Sep 22, 2026 · NCT07296744

A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07521007

Tezspire Cardiac Events PASS

RecruitingObservational study
Ages 12 to 130 · All sexes · Updated Sep 18, 2026 · NCT06951867

Product Surveillance Registry

RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Factors Affect Outcomes in Cardiovascular Surgery

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT01932411

Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy

RecruitingObservational studyHealthy volunteers welcome
Ages 20 to 80 · All sexes · Updated Sep 14, 2026 · NCT06814587

Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.

RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 11, 2026 · NCT07048808

Prognostic Value of Hyperpolarized 13C MRI for Clinical Myocardial Viability

RecruitingObservational studyHealthy volunteers welcome
Ages 20 to 80 · All sexes · Updated Sep 11, 2026 · NCT06047028

Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia

Recruiting
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05111288

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06399692

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06399705

A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Sep 2, 2026 · NCT06164730

Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention

Recruiting
Ages 22 and older · All sexes · Updated Aug 27, 2026 · NCT07691502

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT03504956

Randomization of Single vs Multiple Arterial Grafts

Recruiting
Ages 18 to 70 · All sexes · Updated Aug 20, 2026 · NCT03217006

Progress Complication

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05100940

Progress Bifurcation Global Registry

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05100992

Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

RecruitingObservational study
All ages · All sexes · Updated Aug 19, 2026 · NCT02061436

Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma

Recruiting
Ages 55 and older · All sexes · Updated Aug 7, 2026 · NCT07704918

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.