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COVID-19 and Coronavirus Infections clinical trials recruiting in the U.S.
25 studies for COVID-19 and Coronavirus Infections are recruiting participants at sites across the United States.
Cities with the most studies
- Washington, DC7 studies
- Houston, TX6 studies
- Dallas, TX5 studies
- Hialeah, FL5 studies
- New York City, NY5 studies
- Durham, NC5 studies
- Atlanta, GA4 studies
- Boston, MA4 studies
- Seattle, WA4 studies
- Chicago, IL4 studies
- Los Angeles, CA4 studies
- Salt Lake City, UT3 studies
- Cleveland, OH3 studies
- Cincinnati, OH3 studies
- Pittsburgh, PA3 studies
- Miami, FL3 studies
- Boise, ID3 studies
- San Francisco, CA3 studies
- Richmond, VA3 studies
- Mountain View, CA3 studies
- Louisville, KY3 studies
By state
- Alabama3 studies
- California13 studies
- Colorado4 studies
- District of Columbia3 studies
- Florida7 studies
- Georgia5 studies
- Idaho3 studies
- Illinois6 studies
- Kentucky4 studies
- Maryland7 studies
- Massachusetts4 studies
- Michigan5 studies
- Minnesota3 studies
- New York7 studies
- North Carolina6 studies
- Ohio8 studies
- Pennsylvania5 studies
- South Carolina3 studies
- Tennessee4 studies
- Texas10 studies
- Utah5 studies
- Virginia5 studies
- Washington4 studies
Recently updated studies
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 in Participants ≥6 Months to <12 Years of Age
RecruitingPhase 2Healthy volunteers welcome
6 Months – 11 Years · All sexes · Updated Nov 9, 2026 · NCT07808697A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Formulations
RecruitingPhase 4Healthy volunteers welcome
Ages 12 and older · All sexes · Updated Nov 4, 2026 · NCT07863635Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT05624450Viral Infections in Healthy and Immunocompromised Hosts
RecruitingObservational studyHealthy volunteers welcome
6 Months – 120 Years · All sexes · Updated Oct 29, 2026 · NCT01306084A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Oct 15, 2026 · NCT06679140A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT07013474Determinants of SARS (Severe Acute Respiratory Syndrome)-COV2 (COVID-19) Persistence After Convalescence
RecruitingObservational study
Ages 7 and older · All sexes · Updated Oct 5, 2026 · NCT04448145A Study of COVID-19 Vaccine(s) in Children and Adults
RecruitingPhase 3Healthy volunteers welcome
Ages 5 and older · All sexes · Updated Sep 28, 2026 · NCT07798648Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06631287Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 9, 2026 · NCT04772170Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses
RecruitingPhase 1/2Healthy volunteers welcome
Ages 40 to 64 · All sexes · Updated Aug 18, 2026 · NCT06810934Respiratory Virus Sampling and Repository
RecruitingObservational study
Ages 3 and older · All sexes · Updated Aug 17, 2026 · NCT05266222A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 64 · All sexes · Updated Aug 7, 2026 · NCT07730450Long-term Impact of Infection With Novel Coronavirus (COVID-19)
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Jul 23, 2026 · NCT04362150COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Jun 24, 2026 · NCT04391816Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
RecruitingPhase 3
All ages · All sexes · Updated Jun 23, 2026 · NCT03808922Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT01904188Impact of the Coronavirus (COVID-19) on Patients With Cancer
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Apr 27, 2026 · NCT04330521ARMOR Study: COVID-19 Seroprevalence Among Healthcare Workers
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT04367857A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations
RecruitingPhase 4Healthy volunteers welcome
6 Months · All sexes · Updated Mar 27, 2026 · NCT06585241Understanding Immunity to the Flu Vaccine in COVID-19 Patients
RecruitingObservational studyHealthy volunteers welcome
Ages 9 to 64 · All sexes · Updated Mar 18, 2026 · NCT04579588Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study
RecruitingHealthy volunteers welcome
Ages 18 to 60 · All sexes · Updated Sep 5, 2025 · NCT05868239Phase 2 Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 28, 2021 · NCT04445285Clazakizumab vs. Placebo - COVID-19 Infection
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 31, 2020 · NCT04494724From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.