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Diabetic Foot clinical trials recruiting in the U.S.
49 studies for Diabetic Foot are recruiting participants at sites across the United States.
Over time, high blood sugar from diabetes can damage your nerves or blood vessels. This can lead to foot problems. Know how to care for diabetic feet.
Cities with the most studies
- Miami, FL8 studies
- Pittsburgh, PA7 studies
- Los Angeles, CA7 studies
- Houston, TX6 studies
- St. Louis, MO5 studies
- Coral Springs, FL4 studies
- Atlanta, GA4 studies
- Roanoke, VA4 studies
- Kendall, FL4 studies
- Columbus, OH4 studies
- Pompano Beach, FL3 studies
- Tulsa, OK3 studies
- Vista, CA3 studies
- Tucson, AZ3 studies
- Fresno, CA3 studies
By state
- Arizona5 studies
- California14 studies
- Florida14 studies
- Georgia6 studies
- Illinois3 studies
- Michigan3 studies
- Missouri3 studies
- New York6 studies
- North Carolina4 studies
- Ohio7 studies
- Oklahoma4 studies
- Pennsylvania9 studies
- Texas12 studies
- Virginia4 studies
Recently updated studies
a Prospective, Multicenter, Randomized Controlled Trial, With a Non-randomized Sentinel Cohort, Evaluating the Efficacy of Bioxheal, a Single-layer Placental-derived Biologic in Nonhealing Diabetic Foot Ulcers
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07852338Total Contact Soft Cast in Diabetic Foot Ulcers
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04210089Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers
Recruiting
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07364630Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.
RecruitingPhase 4
Ages 21 and older · All sexes · Updated Sep 22, 2026 · NCT06826339Transverse Tibial Bone Transport (TTT) in the Management of Chronic Diabetic Lower Extremity Wounds
Recruiting
Ages 22 and older · All sexes · Updated Sep 14, 2026 · NCT07444593DFC 004 Biomarkers for Active Diabetic Foot Ulcers
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06104969Diabetic Foot Ulcer Imaging- Study 2
Recruiting
Ages 21 to 100 · All sexes · Updated Sep 4, 2026 · NCT03942081Phase 1 Study of VELGRAFT, a Living Cellular Construct, in the Management of Chronic Diabetic Foot Ulcers Which Have Attained Granulation Tissue
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07498218CARE-D-FOOT-Nav Pilot
Recruiting
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143175Phase 2a Dose Finding Study of Nu-3 Gel in Subjects With Mild iDFU
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07565506Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.
Recruiting
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06437028Miro3D Wound Matrix for Treatment of Diabetic Foot Ulcers
Recruiting
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07632001Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers
Recruiting
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT07161830CAMPR-II RWE TRIAL: A Saline-hydrated Allogeneic Dual-layer Amniotic Membrane Product or a Synthetic, Resorbable Polymeric Wound Matrix to a Coarsened Exact Matched Retrospective Control Cohort of Hard to Heal DFUs and VLUs
Recruiting
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07701590WIREDUP: Wearable Insoles for Recurrent Diabetic Ulcer Prevention
Recruiting
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT05950659Exercise Enhances Wound Healing in Patients With Diabetic Foot Ulcers
Recruiting
Ages 20 to 80 · All sexes · Updated Jun 11, 2026 · NCT04791449Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy
RecruitingPhase 4
Ages 18 and older · All sexes · Updated May 19, 2026 · NCT07086443Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain
RecruitingEarly phase 1
Ages 25 to 75 · All sexes · Updated Apr 20, 2026 · NCT07260656Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC
Recruiting
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06515093A Prospective Clinical Study to Evaluate the Effectiveness and Safety of Xcell Amnio MatrixTM (XAM) in the Management of Chronic Non-healing DFUs
Recruiting
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07116174Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT05172089Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs
Recruiting
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06449638Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
Recruiting
Ages 22 to 90 · All sexes · Updated Feb 17, 2026 · NCT05758545Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Feb 12, 2026 · NCT07396376A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Feb 11, 2026 · NCT07159282From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.