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Diffuse Scleroderma clinical trials recruiting in the U.S.
22 studies for Diffuse Scleroderma are recruiting participants at sites across the United States.
Cities with the most studies
- New York City, NY8 studies
- Chicago, IL7 studies
- Ann Arbor, MI7 studies
- Durham, NC6 studies
- Los Angeles, CA6 studies
- Baltimore, MD5 studies
- Houston, TX5 studies
- Boston, MA5 studies
- Pittsburgh, PA4 studies
- Kansas City, KS4 studies
- New Orleans, LA4 studies
- Philadelphia, PA4 studies
- Charleston, SC3 studies
- Cedar Rapids, IA3 studies
- Aurora, CO3 studies
- Charlotte, NC3 studies
- Jacksonville, FL3 studies
- Phoenix, AZ3 studies
- Plantation, FL3 studies
- Dallas, TX3 studies
By state
- Arizona5 studies
- California9 studies
- Colorado3 studies
- Florida8 studies
- Illinois8 studies
- Iowa3 studies
- Kansas5 studies
- Louisiana4 studies
- Maryland5 studies
- Massachusetts5 studies
- Michigan7 studies
- Minnesota4 studies
- New Jersey3 studies
- New York9 studies
- North Carolina8 studies
- Pennsylvania6 studies
- South Carolina3 studies
- Tennessee4 studies
- Texas7 studies
Recently updated studies
A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Sep 28, 2026 · NCT06470048Sildenafil for Early Pulmonary Vascular Disease in Scleroderma
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT04797286EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07287670A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
RecruitingPhase 1
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06716606A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05878717A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Aug 28, 2026 · NCT06925542Platform Clinical Study for Conquering Scleroderma
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06195072RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis
RecruitingPhase 2/3
Ages 18 to 75 · All sexes · Updated Aug 17, 2026 · NCT06328777Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
RecruitingPhase 2
Ages 8 to 60 · All sexes · Updated Aug 14, 2026 · NCT03630211A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Aug 7, 2026 · NCT06733935AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06991114Diffuse Cutaneous Scleroderma (DSSc) SFDI Study
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07090226A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07115745US Zamto-cel Autoimmune Diseases
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT06708845A Study of Nemolizumab for the Treatment of Adults With Systemic Sclerosis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07047690Rheumatology Patient Registry and Biorepository
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Feb 13, 2026 · NCT04402086Maternal Autoimmune Disease Research Alliance (MADRA) Registry
RecruitingObservational studyHealthy volunteers welcome
All ages · Women · Updated Jan 8, 2026 · NCT03276923The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life
Recruiting
Ages 18 and older · All sexes · Updated Jan 8, 2026 · NCT06675344Scleroderma Registry & Repository at the Hospital for Special Surgery
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 26, 2025 · NCT01656447Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
RecruitingObservational study
All ages · All sexes · Updated May 29, 2025 · NCT01793168Rheumatology Diet Study
RecruitingObservational study
Ages 18 to 65 · All sexes · Updated Dec 6, 2024 · NCT06339957From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.