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Endometrial Cancer clinical trials in Minnesota

42 studies for Endometrial Cancer are looking for participants at sites in Minnesota.

Cities in Minnesota

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

  • Mercy Hospital, Coon Rapids
  • Essentia Health - Deer River Clinic, Deer River
  • Essentia Health Cancer Center, Duluth
  • and 11 more
RecruitingPhase 2
Ages 18 and older · Women · Updated Nov 12, 2026 · NCT05112601

A Study to Evaluate OPB-201 in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.

  • University of Minnesota, Minneapolis
RecruitingPhase 1
Ages 18 and older · Women · Updated Nov 12, 2026 · NCT07664735

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

  • Sanford Joe Lueken Cancer Center, Bemidji
  • Mercy Hospital, Coon Rapids
  • Essentia Health - Deer River Clinic, Deer River
  • and 13 more
RecruitingPhase 2
All ages · All sexes · Updated Nov 12, 2026 · NCT05564377

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

  • Mercy Hospital, Coon Rapids
  • Abbott-Northwestern Hospital, Minneapolis
RecruitingPhase 2
Ages 18 and older · Women · Updated Nov 12, 2026 · NCT05640999

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

  • Minnesota Oncology, Minneapolis
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 10, 2026 · NCT06340568

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

  • Essentia Health Saint Joseph's Medical Center, Brainerd
  • Mercy Hospital, Coon Rapids
  • Essentia Health - Deer River Clinic, Deer River
  • and 12 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 6, 2026 · NCT07198074

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

  • Mayo Clinic, Rochester
RecruitingObservational study
Ages 18 and older · Women · Updated Nov 5, 2026 · NCT05051722

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

  • USOR Minnesota Oncology Hematology, Maplewood
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05579366

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

  • USOR - Minnesota Oncology-Coon Rapids Clinic, Coon Rapids
  • USOR - Minnesota Oncology/ Coon Rapids Clinic, Coon Rapids
  • USOR - Minnesota Oncology - Edina Clinic, Edina
  • and 7 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 3, 2026 · NCT07166094

Molecular and ctDNA Characterization of High-Risk Endometrial Cancer

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Ages 18 and older · Women · Updated Nov 3, 2026 · NCT07062016

Symbiotic-GYN-18: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent MMR-proficient Endometrial Cancer

  • Minnesota Oncology Hematology, PA, Coon Rapids
  • Minnesota Oncology Hematology, PA, Edina
  • Minnesota Oncology Hematology, PA, Maple Grove
  • and 2 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Oct 30, 2026 · NCT07578649

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • Mayo Rochester, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07109726

Avera Cancer Sequencing and Analytics Protocol (ASAP)

  • Avera Cancer Institute - Marshall, Marshall
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT05142033

A Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer in Adjuvant Setting

  • Minnesota Oncology Hematology, P.A., Coon Rapids
RecruitingPhase 3
Ages 18 and older · Women · Updated Oct 27, 2026 · NCT07022483

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

  • M Health Fairview University of Minnesota Medical Center, Minneapolis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06330064

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • Health Partners Frauenshuh Cancer Center, Saint Louis Park
  • Health Partners Cancer Center at Regions Hospital, Saint Paul
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06172478

A Phase 1 Study of the Safety and Tolerability of CTX-10726

  • Mayo Clinic Rochester, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT07419841

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

  • Minnesota Oncology Hematology, Maple Grove
  • Mayo Clinic (Minnesota), Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT04657068

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

  • Research Site, Marshall
  • Research Site, Minneapolis
  • Research Site, Rochester
RecruitingPhase 3
Ages 18 and older · Women · Updated Oct 13, 2026 · NCT06989112

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

  • University of Minnesota, Minneapolis
RecruitingPhase 1
Ages 15 and older · All sexes · Updated Oct 9, 2026 · NCT06276491

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • M Health Fairview University of Minnesota Medical Center, Minneapolis
  • Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 7, 2026 · NCT05919264

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Mayo Clinic (Rochester), Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

  • University of Minnesota Masonic Cancer Center, Minneapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07216105

Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Undergone Radiation Therapy

  • Mayo Clinic in Rochester, Rochester
Recruiting
Ages 21 and older · Women · Updated Aug 31, 2026 · NCT07662824

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

  • University of Minnesota/Masonic Cancer Center, Minneapolis
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

  • Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · Women · Updated Aug 19, 2026 · NCT04567771

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

  • Normunity Investigational Site, Minneapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07182149

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

  • Research Site, Minneapolis
RecruitingPhase 3
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

  • 518, Minneapolis
RecruitingPhase 2
Ages 18 and older · Women · Updated Jul 16, 2026 · NCT06906341

Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection of Endometrial Cancer

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 45 and older · Women · Updated Jul 9, 2026 · NCT07527143

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

  • Mayo Clinic - Rochester, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

Integrated Cancer Repository for Cancer Research

  • Riverwood Healthcare Center, Aitkin
  • Essentia Health-St. Joseph's Medical Center, Brainerd
  • Essentia Health - Duluth Clinic, Duluth
  • and 2 more
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia With an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients With Post-Menopausal Bleeding

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Ages 55 and older · Women · Updated Jun 10, 2026 · NCT06365905

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

  • Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT06349642

Screening and Staging of Benign vs Malignant Pelvic Abnormalities

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07407959

First in Human Study of TORL-1-23 in Participants With Advanced Cancer

  • University of Minnesota, Minneapolis
  • Mayo Clinic in Rochester, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT05103683

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer

  • Minnesota Oncology Hematology, P.A., Maple Grove
RecruitingPhase 2
Ages 18 and older · Women · Updated Dec 24, 2025 · NCT06463028

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.