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Erectile Dysfunction clinical trials recruiting in the U.S.
17 studies for Erectile Dysfunction are recruiting participants at sites across the United States.
Men with erectile dysfunction (ED), or impotence, have trouble getting or keeping an erection. It is more common in older men. Learn about treatment.
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Recently updated studies
Penile Lengthening Pre-Penile Prosthesis Implantation
Recruiting
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07053826Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
Recruiting
Ages 40 and older · Men · Updated Aug 19, 2026 · NCT05868668Evaluation of the Rigicon Infla10® Inflatable Penile Prosthesis (IPP) for Erectile Dysfunction
Recruiting
Ages 22 and older · Men · Updated Aug 13, 2026 · NCT07273773Stem Cells for Erectile Dysfunction Post RALP
RecruitingPhase 1/2
Ages 40 to 70 · Men · Updated Jul 10, 2026 · NCT07048314Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
RecruitingObservational study
All ages · All sexes · Updated Jun 11, 2026 · NCT00499317A Single Arm Study of Extracorporeal Shockwave Therapy for Management of Erectile Dysfunction
Recruiting
Ages 18 and older · Men · Updated May 18, 2026 · NCT07592533Helping Men Adhere to Sexual Rehabilitation Following Prostate Cancer Surgery
Recruiting
Ages 21 and older · Men · Updated Apr 8, 2026 · NCT02706561EndoPAT Device for Endothelial Dysfunction in ED
Recruiting
Ages 18 and older · Men · Updated Feb 2, 2026 · NCT06720597The Impact of a Plant-based Meat Meal Versus an Animal Meat Meal on Erectile Function in Healthy Men.
RecruitingHealthy volunteers welcome
Ages 18 to 32 · Men · Updated Jan 23, 2026 · NCT06273592External Device for Erectile Dysfunction (3D-Erect)
Recruiting
Ages 18 and older · Men · Updated Jan 13, 2026 · NCT04624126Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease
Recruiting
Ages 18 and older · Men · Updated Jan 7, 2026 · NCT060654364-aminopyridine Treatment for Nerve Injury
RecruitingPhase 2/3
Ages 45 to 75 · Men · Updated Dec 17, 2025 · NCT03701581The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fed Versus 100 mg of Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fasted Conditions in Healthy Adult Male Subjects
RecruitingPhase 1Healthy volunteers welcome
Ages 20 to 70 · Men · Updated Nov 19, 2025 · NCT06872866Prostate Stimulation for Sexual Dysfunction
Recruiting
Ages 18 and older · Men · Updated Jun 3, 2025 · NCT05468931Double-S: a Wearable Device for Erectile Dysfunction
Recruiting
Ages 18 and older · Men · Updated May 22, 2025 · NCT05451563SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)
RecruitingPhase 3
Ages 18 and older · Men · Updated Apr 25, 2025 · NCT06945315Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 29, 2022 · NCT04684602From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.