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Glioblastoma clinical trials in Florida
30 studies for Glioblastoma are looking for participants at sites in Florida.
Cities in Florida
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
- Miami Cancer Institute, Miami
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07326566A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
- Sarah Cannon Research Institute at Florida Cancer Specialists- Lake Nona, Orlando
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06914128Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
- Advent Health, Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07195591Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment
- UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
- Mayo Clinic in Florida, Jacksonville
- and 2 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT05432804A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07464925A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
- Sylvester Comprehensive Cancer Center*, Miami
- Moffitt Cancer Center, Tampa
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT03970447A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM
- Mayo Jacksonville, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT05303467A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)
- UF Health, Gainesville
RecruitingPhase 1
Ages 4 and older · All sexes · Updated Oct 30, 2026 · NCT04573140Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT07708961Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma
- UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
- UM Sylvester Comprehensive Cancer Center at Coral Springs, Coral Springs
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
- and 6 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT06860594Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
- Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT06810544Window of Opportunity Study of Lixumistat in Patients With Newly Diagnosed Glioblastoma
- University of Miami, Miami
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT07884344SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
- University of Florida Health, Gainesville
- Mayo Clinic - Florida, Jacksonville
- University of Miami Health, Miami
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT05303519Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma
- Baptist Health Herbert Wertheim Cancer Institute, Miami
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06991101The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07285044Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
- MDR Core Network, Boynton Beach
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial
- UF Health Shands Hospital, Gainesville
RecruitingPhase 2
Ages 18 to 90 · All sexes · Updated Sep 23, 2026 · NCT06558214Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma
- University of Miami (Data collection only), Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06934889Targeted Pediatric High-Grade Glioma Therapy
- University of Miami, Miami
RecruitingObservational study
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379Study of Olutasidenib and Temozolomide in HGG
- University of Miami Hospital and Clinics, Miami
RecruitingPhase 2
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial
- Baptist MD Anderson Cancer Center, Jacksonville
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06319027Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma
- Mayo Clinic in Florida, Jacksonville
Recruiting
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07091864A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial
- Mayo Clinic in Florida, Jacksonville
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07074756Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma
- University of Miami, Miami
Recruiting
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT05284643DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)
- Baptist MD Anderson Cancer Center, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT06805305A Phase 1/2 Study of the Safety and Tolerability of MT-125 in GBM Patients
- Mayo Clinic Hospital, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT07185880Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT05789394Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue
- Miami Cancer Institute at Baptist Health, Inc., Miami
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT05756985Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age
- Jackson Memorial Hospital, Miami
RecruitingPhase 1/2Healthy volunteers welcome
Ages 1 to 21 · All sexes · Updated Dec 8, 2025 · NCT05956821SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Jacksonville
- Massive Bio SYNERGY-AI site, Miami
- Massive Bio SYNERGY-AI site, Tampa
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.