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Glioblastoma clinical trials in Minnesota
19 studies for Glioblastoma are looking for participants at sites in Minnesota.
Cities in Minnesota
Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment
- Mayo Clinic in Rochester, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05432804REMIND Maintenance Radiotherapy for Newly Diagnosed Glioblastoma
- University of Minnesota Radiation Oncology, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07831772SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
- Mayo Clinic - Rochester, Rochester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma
- Mayo Clinic in Rochester, Rochester
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07076472Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions
- Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT04047264Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma
- Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07091864A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial
- Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07074756A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
- Allina Health Systems/Abbott Northwestern Hospital, Minneapolis
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT03970447Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma
- Mayo Clinic, Rochester
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Jul 17, 2026 · NCT07225621Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas
- Mayo Clinic in Rochester, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 24, 2026 · NCT07468136Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab
- Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 19 and older · All sexes · Updated Jun 8, 2026 · NCT06011109First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma
- Elizabeth C. Neil, MD, Minneapolis
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated May 1, 2026 · NCT07560865ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade Glioma
- Mayo Clinic in Rochester, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 21, 2026 · NCT05917145A Phase 1/2 Study of the Safety and Tolerability of MT-125 in GBM Patients
- Mayo Clinic Hospital, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT07185880Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
- Mayo Clinic Cancer Center, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma
- Mayo Clinic in Rochester, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT07301268Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma
- Mayo Clinic, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jan 12, 2026 · NCT05465954SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Duluth
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma
- Mayo Clinic, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 19, 2024 · NCT06160206From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.