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Glioma clinical trials in California

25 studies for Glioma are looking for participants at sites in California.

Cities in California

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

  • Loma Linda University Medical Center, Loma Linda
  • Miller Children's and Women's Hospital Long Beach, Long Beach
  • Children's Hospital Los Angeles, Los Angeles
  • and 7 more
RecruitingPhase 1/2
12 Months โ€“ 21 Years ยท All sexes ยท Updated Sep 30, 2026 ยท NCT05099003

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

  • UCSD Moores Cancer Center, La Jolla
  • Cedars-Sinai Medical Center, Los Angeles
  • Stanford University, Palo Alto
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07326566

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

  • Children's Hospital Los Angeles, Los Angeles
  • University of California at Los Angeles, Los Angeles
RecruitingPhase 1/2
Up to age 25 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT04094610

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

  • Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 21, 2026 ยท NCT04977375

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

  • Children's Hospital Orange County (CHOC), Orange
RecruitingPhase 1
Ages 5 to 18 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06357377

Assessing Brain Metabolism Using MRS With Deuterated Glucose

  • University of California, San Francisco, San Francisco
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 2, 2026 ยท NCT06594315

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

  • University of California San Diego, La Jolla
  • University of California, Los Angeles, Los Angeles
  • Hoag Memorial Hospital Presbyterian, Newport Beach
  • and 2 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 28, 2026 ยท NCT05303519

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

  • Children's Hospital Los Angeles, Los Angeles
  • University of California, San Diego Rady Children's Hospital, San Diego
  • University of California, San Francisco, San Francisco
RecruitingPhase 1
Ages 1 to 25 ยท All sexes ยท Updated Aug 18, 2026 ยท NCT04485559

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

  • Research Site, Los Angeles
  • Research Site, San Francisco
RecruitingPhase 1/2
Ages 18 to 130 ยท All sexes ยท Updated Aug 12, 2026 ยท NCT05417594

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

  • UCI Irvine Health, Orange
RecruitingPhase 4
Ages 18 and older ยท All sexes ยท Updated Aug 11, 2026 ยท NCT07486713

A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3

  • University of California Irvine, Orange
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Aug 11, 2026 ยท NCT05916313

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

  • Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
RecruitingEarly phase 1
Ages 18 and older ยท All sexes ยท Updated Jul 31, 2026 ยท NCT07628634

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

  • Precision NextGen Oncology & Research Center, Beverly Hills
  • UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco
  • University of California Los Angeles Rheumatology, Westwood, Los Angeles
RecruitingPhase 2
Ages 8 and older ยท All sexes ยท Updated Jul 27, 2026 ยท NCT05503797

Imaging of Solid Tumors Using 18F-TRX

  • University of California, San Francisco, San Francisco
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Jul 23, 2026 ยท NCT06942104

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

  • Stanford University School of Medicine, Palo Alto
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Jun 29, 2026 ยท NCT03510208

Hyperpolarized Imaging in Diagnosing Participants With Glioma

  • University of California, San Francisco, San Francisco
RecruitingPhase 1
Ages 19 and older ยท All sexes ยท Updated Jun 18, 2026 ยท NCT03739411

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

  • Moores Cancer Center, San Diego
RecruitingObservational study
Ages 18 to 99 ยท All sexes ยท Updated Jun 10, 2026 ยท NCT05576103

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

  • University of California, San Francisco, San Francisco
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Apr 29, 2026 ยท NCT04540107

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

  • UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco
  • UCLA Hematology/Oncology, Westwood, Los Angeles
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Apr 20, 2026 ยท NCT06326411

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

  • University of California, Irvine, Irvine
  • University of California Los Angeles, Los Angeles
  • University of California at San Francisco, San Francisco
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Apr 13, 2026 ยท NCT06810544

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

  • Children's Health Orange County (CHOC), Orange
RecruitingPhase 1
12 Months โ€“ 18 Years ยท All sexes ยท Updated Mar 17, 2026 ยท NCT04943848

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

  • University of Southern California, Los Angeles
  • University of California, San Diego, San Diego
  • University of California, San Francisco
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Mar 11, 2026 ยท NCT06504381

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Feb 5, 2026 ยท NCT06650163

MCT for the Harvard/UCSF ROBIN Center

  • University of California, San Francisco, San Francisco
Recruiting
All ages ยท All sexes ยท Updated Feb 17, 2025 ยท NCT06000787

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

  • University of California, San Francisco (UCSF), San Francisco
RecruitingObservational study
Ages 18 to 90 ยท All sexes ยท Updated Feb 22, 2024 ยท NCT06118723

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.