Glioma clinical trials in Florida
23 studies for Glioma are looking for participants at sites in Florida.
Cities in Florida
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
- Miami Cancer Institute, Miami
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
- Golisano Children's Hospital of Southwest Florida, Fort Myers
- Nemours Children's Clinic-Jacksonville, Jacksonville
- University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami
- and 4 more
RecruitingPhase 1/2
12 Months – 21 Years · All sexes · Updated Sep 25, 2026 · NCT05099003ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
- Nicklaus Children's Hospital, Miami
RecruitingPhase 2
12 Months – 39 Years · All sexes · Updated Sep 21, 2026 · NCT06838676Targeted Pediatric High-Grade Glioma Therapy
- University of Miami, Miami
RecruitingObservational study
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379Study of Olutasidenib and Temozolomide in HGG
- University of Miami Hospital and Clinics, Miami
RecruitingPhase 2
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
- University of Florida Health, Gainesville
- Mayo Clinic - Florida, Jacksonville
- University of Miami Health, Miami
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
- Nicklaus Children's Hospital, Miami
RecruitingPhase 2
Ages 3 to 39 · All sexes · Updated Aug 24, 2026 · NCT05096481Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
- University of Florida, Gainesville
RecruitingPhase 1
Ages 1 to 25 · All sexes · Updated Aug 18, 2026 · NCT04485559Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05030298A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial
- Mayo Clinic in Florida, Jacksonville
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07074756A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07464925A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
- University of Miami Hospital and Clinics, Miami
RecruitingPhase 2
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797Pembrolizumab, Olaparib, and Temozolomide for People With Glioma
- BAPTIST ALLIANCE - MCI (Data Collection Only), Miami
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05188508STARLITE for Unresectable High-Grade Gliomas
- University of Miami, Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06428045A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)
- UF Health, Gainesville
RecruitingPhase 1
Ages 4 and older · All sexes · Updated Jun 25, 2026 · NCT04573140PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial
- Lynn Cancer Institute at Baptist Health, Inc., Boca Raton
- Miami Cancer Institute at Baptist Health, Inc., Miami
Recruiting
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT06397560DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma
- University of Miami Hospital, Miami
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated May 28, 2026 · NCT06264388Non-invasive Glioma Characterization Through Molecular Imaging
- University of Miami, Miami
Recruiting
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT03684109A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06326411Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
- Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma.
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06482905DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma
- University of Miami, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 11, 2026 · NCT06504381Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
- University of Miami Hospital, Miami
RecruitingPhase 1/2
Up to age 18 · All sexes · Updated Nov 20, 2025 · NCT04299191From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.