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Hemoglobinopathies clinical trials recruiting in the U.S.

14 studies for Hemoglobinopathies are recruiting participants at sites across the United States.

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Recently updated studies

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling

RecruitingEarly phase 1
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT06313398

Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases

RecruitingPhase 1/2
Up to age 20 · All sexes · Updated Sep 16, 2026 · NCT00920972

Long Term Follow-Up Study for Individuals With Hemoglobin Disorders After Hematopoietic Cell Transplant or Gene Therapy

RecruitingObservational study
All ages · All sexes · Updated Sep 15, 2026 · NCT06646640

The HOPE Biobank Resource (BMT CTN 2402 HOPE)

RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Aug 27, 2026 · NCT07227155

Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

Recruiting
Up to age 55 · All sexes · Updated Jul 6, 2026 · NCT01666080

TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children

RecruitingPhase 2
Ages 0 to 21 · All sexes · Updated Jul 1, 2026 · NCT04356469

Allo HSCT for High Risk Hemoglobinopathies

RecruitingPhase 2Healthy volunteers welcome
Up to age 55 · All sexes · Updated Jun 4, 2026 · NCT06872333

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

RecruitingPhase 1/2
1 Day – 21 Years · All sexes · Updated May 29, 2026 · NCT03128996

Discarded Bone Marrow for Hematology Research

RecruitingObservational study
All ages · All sexes · Updated May 5, 2026 · NCT04671212

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

RecruitingPhase 1/2
1 Month – 25 Years · All sexes · Updated Apr 15, 2026 · NCT06839456

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

RecruitingPhase 2
Up to age 21 · All sexes · Updated Mar 13, 2026 · NCT04644016

A Long-term Follow-up Study in Patients Who Received BEAM-101

RecruitingObservational study
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639

Study of the Role of Genetic Modifiers in Hemoglobinopathies

RecruitingObservational study
Ages 2 and older · All sexes · Updated Mar 20, 2024 · NCT05799118

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.