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Hemophilia clinical trials recruiting in the U.S.

28 studies for Hemophilia are recruiting participants at sites across the United States.

Hemophilia is a rare disorder in which the blood does not clot normally. Usually hemophilia usually occurs in males and is inherited. Learn more.

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Recently updated studies

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

RecruitingPhase 3
Ages 1 to 17 · Men · Updated Sep 23, 2026 · NCT05611801

A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A

RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 23, 2026 · NCT07416526

Treatment of Hemophilia A Patients With FVIII Inhibitors

RecruitingObservational study
All ages · Men · Updated Sep 23, 2026 · NCT04023019

A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 64 · Men · Updated Sep 18, 2026 · NCT07220564

A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT07226206

A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 4, 2026 · NCT07416604

SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis

RecruitingPhase 3
Ages 6 and older · All sexes · Updated Aug 21, 2026 · NCT04563520

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

RecruitingPhase 3
Ages 1 to 74 · Men · Updated Jul 1, 2026 · NCT05145127

Efficacy, Safety & Utilisation of Nuwiq, Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A Patients

RecruitingObservational study
All ages · All sexes · Updated Jun 2, 2026 · NCT03695978

Nuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing FVIII Treatment for Surgery

RecruitingPhase 4
Ages 12 and older · Women · Updated May 12, 2026 · NCT05936580

Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study

RecruitingPhase 4
Ages 12 and older · Men · Updated May 12, 2026 · NCT05935358

ATHNdataset Registry

RecruitingObservational study
All ages · All sexes · Updated Apr 21, 2026 · NCT06820515

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

RecruitingPhase 1
Ages 0 to 90 · All sexes · Updated Apr 3, 2026 · NCT05500807

Hemophilia A Research Program

RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Feb 17, 2026 · NCT07414511

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

RecruitingPhase 4
Ages 12 to 100 · All sexes · Updated Jan 12, 2026 · NCT04647227

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.