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Hereditary Spastic Paraplegia clinical trials recruiting in the U.S.
6 studies for Hereditary Spastic Paraplegia are recruiting participants at sites across the United States.
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Recently updated studies
Neuromodulation to Enhance Motor Function in HSP
Recruiting
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07417943Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
RecruitingObservational studyHealthy volunteers welcome
Up to age 30 · All sexes · Updated Mar 18, 2026 · NCT04712812Spastic Paraplegia - Centers of Excellence Research Network
RecruitingObservational study
All ages · All sexes · Updated Mar 18, 2026 · NCT06553976Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
RecruitingObservational study
1 Month – 30 Years · All sexes · Updated Mar 18, 2026 · NCT05354622Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease
Recruiting
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT07478172Natural History Study of Patients with HPDL Mutations
RecruitingObservational study
All ages · All sexes · Updated Mar 30, 2025 · NCT05848271From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.