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Hereditary Spastic Paraplegia clinical trials recruiting in the U.S.

6 studies for Hereditary Spastic Paraplegia are recruiting participants at sites across the United States.

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Recently updated studies

Neuromodulation to Enhance Motor Function in HSP

Recruiting
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07417943

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

RecruitingObservational studyHealthy volunteers welcome
Up to age 30 · All sexes · Updated Mar 18, 2026 · NCT04712812

Spastic Paraplegia - Centers of Excellence Research Network

RecruitingObservational study
All ages · All sexes · Updated Mar 18, 2026 · NCT06553976

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

RecruitingObservational study
1 Month – 30 Years · All sexes · Updated Mar 18, 2026 · NCT05354622

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease

Recruiting
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT07478172

Natural History Study of Patients with HPDL Mutations

RecruitingObservational study
All ages · All sexes · Updated Mar 30, 2025 · NCT05848271

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.