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Homozygous Familial Hypercholesterolemia clinical trials recruiting in the U.S.
7 studies for Homozygous Familial Hypercholesterolemia are recruiting participants at sites across the United States.
Recently updated studies
Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia
RecruitingPhase 3
Ages 12 to 17 · All sexes · Updated Oct 26, 2026 · NCT07473843The ORIGIN-FH Study
Recruiting
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07470723Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
RecruitingPhase 3
Ages 2 to 100 · All sexes · Updated Sep 18, 2026 · NCT05682378A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07491172Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
RecruitingPhase 3
Ages 2 to 11 · All sexes · Updated Jul 24, 2026 · NCT06597006The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository
RecruitingObservational study
All ages · All sexes · Updated Apr 6, 2026 · NCT01109368HoFH, the International Clinical Collaborators Registry
RecruitingObservational study
All ages · All sexes · Updated Dec 18, 2025 · NCT04815005From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.