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Intervertebral Disc Degeneration clinical trials recruiting in the U.S.

22 studies for Intervertebral Disc Degeneration are recruiting participants at sites across the United States.

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Recently updated studies

HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs

Recruiting
Ages 22 to 85 · All sexes · Updated Sep 18, 2026 · NCT06011551

ACDF Using Structural Allograft vs. Tritanium C

Recruiting
Ages 18 to 80 · All sexes · Updated Aug 31, 2026 · NCT04388332

LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)

RecruitingPhase 1/2
Ages 22 to 80 · All sexes · Updated Aug 26, 2026 · NCT06462729

Biologic Injection For Adults With Lumbar Disc Herniation

Recruiting
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT07386548

Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06438471

Clinical Outcome Measure at Stryker Spine

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT06226272

OssDsign® Spine Registry Study ("Propel")

RecruitingObservational study
Ages 21 and older · All sexes · Updated Jun 8, 2026 · NCT05329129

Brain Mechanisms Supporting Cannabis-induced Pain Relief

RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 to 65 · All sexes · Updated Jun 3, 2026 · NCT04982965

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Feb 17, 2026 · NCT05029726

Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty

RecruitingObservational study
Ages 18 to 60 · All sexes · Updated Feb 13, 2026 · NCT05701059

Conduit Cages and Fibergraft BG Putty

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT06704919

OssiMend BA in Posterolateral Instrumented Lumbar Fusion

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 16, 2025 · NCT04775537

Trial for Treating Painful Degenerative Disc Disease

Recruiting
Ages 25 to 65 · All sexes · Updated Apr 6, 2025 · NCT05287867

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 24, 2024 · NCT05648474

Personalized Spine Study Group (PSSG) Registry

RecruitingObservational study
Ages 10 to 85 · All sexes · Updated Oct 3, 2024 · NCT04601363

Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers

RecruitingHealthy volunteers welcome
Ages 21 to 85 · All sexes · Updated Sep 28, 2023 · NCT03076658

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.