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Intervertebral Disc Degeneration clinical trials recruiting in the U.S.
22 studies for Intervertebral Disc Degeneration are recruiting participants at sites across the United States.
Cities with the most studies
- Nashville, TN3 studies
- Philadelphia, PA3 studies
- Miami, FL3 studies
- Santa Monica, CA3 studies
- Shreveport, LA3 studies
By state
- California11 studies
- Colorado5 studies
- Connecticut3 studies
- Florida6 studies
- Georgia3 studies
- Indiana3 studies
- Louisiana4 studies
- Michigan4 studies
- New York3 studies
- North Carolina4 studies
- Ohio4 studies
- Pennsylvania6 studies
- Tennessee4 studies
- Texas6 studies
- Virginia3 studies
Recently updated studies
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 23, 2026 · NCT07254806HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs
Recruiting
Ages 22 to 85 · All sexes · Updated Sep 18, 2026 · NCT06011551Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
Recruiting
Ages 22 to 85 · All sexes · Updated Sep 14, 2026 · NCT06778447ACDF Using Structural Allograft vs. Tritanium C
Recruiting
Ages 18 to 80 · All sexes · Updated Aug 31, 2026 · NCT04388332LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)
RecruitingPhase 1/2
Ages 22 to 80 · All sexes · Updated Aug 26, 2026 · NCT06462729Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease
RecruitingPhase 3
Ages 21 to 80 · All sexes · Updated Aug 26, 2026 · NCT07017634Biologic Injection For Adults With Lumbar Disc Herniation
Recruiting
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT07386548Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06438471MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
Recruiting
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05037968Clinical Outcome Measure at Stryker Spine
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT06226272OssDsign® Spine Registry Study ("Propel")
RecruitingObservational study
Ages 21 and older · All sexes · Updated Jun 8, 2026 · NCT05329129Brain Mechanisms Supporting Cannabis-induced Pain Relief
RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 to 65 · All sexes · Updated Jun 3, 2026 · NCT04982965Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion
Recruiting
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT04679844Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Feb 17, 2026 · NCT05029726Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty
RecruitingObservational study
Ages 18 to 60 · All sexes · Updated Feb 13, 2026 · NCT05701059Conduit Cages and Fibergraft BG Putty
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT06704919OssiMend BA in Posterolateral Instrumented Lumbar Fusion
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 16, 2025 · NCT04775537Trial for Treating Painful Degenerative Disc Disease
Recruiting
Ages 25 to 65 · All sexes · Updated Apr 6, 2025 · NCT05287867Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.
Recruiting
Ages 22 to 69 · All sexes · Updated Jan 27, 2025 · NCT06485206Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 24, 2024 · NCT05648474Personalized Spine Study Group (PSSG) Registry
RecruitingObservational study
Ages 10 to 85 · All sexes · Updated Oct 3, 2024 · NCT04601363Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
RecruitingHealthy volunteers welcome
Ages 21 to 85 · All sexes · Updated Sep 28, 2023 · NCT03076658From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.