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Itching clinical trials recruiting in the U.S.
15 studies for Itching are recruiting participants at sites across the United States.
Pruritus, or itchy skin, is tingling or irritation that makes you want to scratch the area. It's a symptom of many health conditions. Learn the causes.
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Recently updated studies
Cervical Traction to Reduce Gabaergic Medication Use for Neuropathic Itch
Recruiting
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06751056Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa
RecruitingPhase 3
28 Days – 12 Years · All sexes · Updated Sep 4, 2026 · NCT07482787A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
RecruitingPhase 3
Ages 12 to 17 · All sexes · Updated Sep 3, 2026 · NCT06979453Cardamom and Topical Roseomonas in Atopic Dermatitis
RecruitingPhase 2
Ages 2 to 100 · All sexes · Updated Aug 13, 2026 · NCT06096857Obtaining Descriptive Classifications of Pruritus and Assessing Change in Pruritus Over Time in Atopic Dermatitis Patients Using Topical Roflumilast Cream.
RecruitingPhase 4
Ages 12 and older · All sexes · Updated Aug 13, 2026 · NCT07560618Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)
RecruitingPhase 3
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT05263206TriCalm Hydrogel® in the Treatment of Immunotherapy-Related Pruritus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06748404A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT07219615Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin Disorders
RecruitingEarly phase 1
6 Months · All sexes · Updated May 1, 2026 · NCT05649098VR-PMR for Post-Burn Symptoms
Recruiting
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT07317271An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis
RecruitingObservational study
Ages 14 and older · Women · Updated Dec 11, 2025 · NCT06627335Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population
RecruitingObservational study
Ages 15 to 50 · Women · Updated Dec 11, 2025 · NCT06259669A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSC
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 24, 2025 · NCT06699121Novel Strategies for Reducing Burn Scar Itch
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Sep 24, 2025 · NCT06801626Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinic
RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated Sep 19, 2025 · NCT06226610From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.