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Lung Cancer clinical trials in Iowa

21 studies for Lung Cancer are looking for participants at sites in Iowa.

Cities in Iowa

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

  • Mary Greeley Medical Center, Ames
  • McFarland Clinic - Ames, Ames
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • and 13 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06498635

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

  • Mary Greeley Medical Center, Ames
  • McFarland Clinic - Ames, Ames
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • and 14 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04267848

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • Mercy Hospital, Cedar Rapids
  • Oncology Associates at Mercy Medical Center, Cedar Rapids
  • and 7 more
RecruitingPhase 3
Ages 70 and older · All sexes · Updated Nov 12, 2026 · NCT06096844

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

  • University of Iowa, Iowa City
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT04198766

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mary Greeley Medical Center, Ames
  • McFarland Clinic - Ames, Ames
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • and 12 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

  • Mary Greeley Medical Center, Ames
  • McFarland Clinic - Ames, Ames
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • and 10 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT04181060

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)

  • Physicians Clinic of Iowa, Cedar Rapids
  • Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT06712316

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

  • University of Iowa Health Care, Iowa City
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT06922591

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

  • McFarland Clinic, Ames
  • Helen G. Nassif Community Cancer Center, Cedar Rapids
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06712355

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

  • Mary Greeley Medical Center, Ames
  • McFarland Clinic - Ames, Ames
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • and 8 more
RecruitingPhase 2
18 Minutes · All sexes · Updated Oct 9, 2026 · NCT06031688

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

  • University of Iowa Healthcare Cancer Services Quad Cities, Bettendorf
  • Physicians' Clinic of Iowa PC, Cedar Rapids
  • University of Iowa/Holden Comprehensive Cancer Center, Iowa City
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT06616584

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

  • Local Institution - 0065, Iowa City
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

  • Mary Greeley Medical Center, Ames
  • McFarland Clinic - Ames, Ames
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • and 12 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Integrated Cancer Repository for Cancer Research

  • Methodist Jennie Edmundson Hospital, Council Bluffs
  • Covenant Medical Center, Inc, Waterloo
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

CHAMP Lung Cancer Screening Program

  • University of Iowa, Iowa City
  • Cedar Valley Primary Care & Walk-In Clinic, Waterloo
  • Greenwood Pharmacy and Compounding Center, Waterloo
Recruiting
Ages 50 to 77 · All sexes · Updated Jun 16, 2026 · NCT07572773

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

  • UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny
  • UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive
  • Iowa Methodist Medical Center, Des Moines
  • and 4 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

  • University of Iowa Hospitals and Clinics, Iowa City
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT04919382

Using Xe MRI to Guide Radiation Therapy for Lung Cancer

  • University of Iowa, Iowa City
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Jan 2, 2026 · NCT06925295

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Iowa City
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.