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Lung Cancer clinical trials in Saint Paul, MN

13 studies for Lung Cancer are looking for participants at sites in and around Saint Paul (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Saint John's Hospital - Healtheast, Maplewood · 5 mi away
Ages 70 and older · All sexes · Updated Sep 30, 2026 · NCT06096844

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT04181060

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06498635

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Allina Health Cancer Institute - United Hospital, Saint Paul
  • Minnesota Oncology Hematology, P.A., Maplewood · 5 mi away
  • Minnesota Oncology Hematology, P.A., Woodbury · 7 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • M Health Fairview St. John's Hospital, Maplewood · 5 mi away
  • Minnesota Oncology Hematology PA, Maplewood · 5 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Health Partners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • HealthPartners Cancer Research Center, Saint Paul
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Axelopran for Advanced Cancer in Patients Receiving Opioids

RecruitingPhase 2
  • HealthPartners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07354919

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Woodbury, Woodbury · 7 mi away
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Saint Paul

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.