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Lupus Nephritis clinical trials recruiting in the U.S.

33 studies for Lupus Nephritis are recruiting participants at sites across the United States.

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Recently updated studies

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

RecruitingPhase 1/2
Ages 10 to 29 · All sexes · Updated Sep 24, 2026 · NCT06839976

A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis

RecruitingPhase 2
Ages 16 to 70 · All sexes · Updated Sep 17, 2026 · NCT07328581

VIBRANT: VIB4920 for Active Lupus Nephritis

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05201469

Study of Systemic Lupus Erythematosus

RecruitingObservational studyHealthy volunteers welcome
Ages 3 to 120 · All sexes · Updated Sep 16, 2026 · NCT00001372

Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis

RecruitingPhase 1
Ages 18 to 60 · All sexes · Updated Sep 14, 2026 · NCT06975787

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

RecruitingPhase 2
Ages 8 to 20 · All sexes · Updated Sep 14, 2026 · NCT05538208

A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis

RecruitingPhase 2
Ages 12 to 70 · All sexes · Updated Sep 14, 2026 · NCT07570862

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

RecruitingPhase 1/2
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT06897930

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Aug 28, 2026 · NCT06925542

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)

RecruitingPhase 2
Ages 12 to 65 · All sexes · Updated Aug 24, 2026 · NCT07053800

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

RecruitingPhase 2
Ages 16 and older · All sexes · Updated Aug 4, 2026 · NCT06419205

PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis

RecruitingPhase 4
Ages 18 to 75 · All sexes · Updated Aug 3, 2026 · NCT07611214

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Jul 30, 2026 · NCT05268289

A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment

RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Jul 30, 2026 · NCT07201129

Wellness & Workforce Solution for Lupus/Lupus Nephritis

RecruitingHealthy volunteers welcome
Ages 18 and older · Women · Updated Jul 24, 2026 · NCT06217107

A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07115745

Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT06527872

US Zamto-cel Autoimmune Diseases

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT06708845

A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)

RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Jun 4, 2026 · NCT06557265

Dapagliflozin in Active Lupus Nephritis

RecruitingPhase 4
Ages 18 to 70 · All sexes · Updated May 26, 2026 · NCT07323524

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

RecruitingPhase 1
Ages 12 to 70 · All sexes · Updated May 22, 2026 · NCT06308978

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.