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Mania clinical trials recruiting in the U.S.

5 studies for Mania are recruiting participants at sites across the United States.

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Recently updated studies

An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania

RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 29, 2026 · NCT07288320

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 24, 2026 · NCT06951711

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT06951698

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT06929273

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.