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Medulloblastoma clinical trials recruiting in the U.S.

23 studies for Medulloblastoma are recruiting participants at sites across the United States.

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Recently updated studies

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

RecruitingPhase 1/2
Ages 18 to 120 · All sexes · Updated Nov 6, 2026 · NCT06161519

Digoxin Medulloblastoma Study

RecruitingPhase 2
12 Months – 30 Years · All sexes · Updated Nov 4, 2026 · NCT06701812

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

RecruitingPhase 1
Ages 3 to 25 · All sexes · Updated Nov 2, 2026 · NCT05106296

68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.

RecruitingPhase 4
Ages 18 to 100 · All sexes · Updated Oct 30, 2026 · NCT04081701

Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)

RecruitingPhase 1
Ages 1 to 30 · All sexes · Updated Oct 13, 2026 · NCT06193759

Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors

RecruitingPhase 2
Up to age 19 · All sexes · Updated Oct 13, 2026 · NCT01356290

GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults

RecruitingPhase 1
Ages 1 to 30 · All sexes · Updated Oct 9, 2026 · NCT07087002

Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease

RecruitingPhase 1/2
Ages 1 to 25 · All sexes · Updated Sep 28, 2026 · NCT07346157

Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic Neurofeedback

Recruiting
Ages 10 to 25 · All sexes · Updated Sep 23, 2026 · NCT07830134

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

RecruitingPhase 2
59 Months · All sexes · Updated Sep 15, 2026 · NCT05535166

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

RecruitingPhase 1
36 Months – 22 Years · All sexes · Updated Sep 4, 2026 · NCT03911388

B7-H3.CD28Z.CART in CNS Neoplasms

RecruitingPhase 1
Ages 2 to 21 · All sexes · Updated Sep 3, 2026 · NCT07390539

Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study

RecruitingObservational study
Ages 3 to 50 · All sexes · Updated Sep 1, 2026 · NCT07242963

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

RecruitingPhase 3
Ages 4 to 21 · All sexes · Updated Aug 25, 2026 · NCT05382338

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

RecruitingPhase 2
Ages 3 to 39 · All sexes · Updated Aug 24, 2026 · NCT05096481

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

RecruitingPhase 2
Up to age 21 · All sexes · Updated Aug 12, 2026 · NCT04696029

Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma

Recruiting
12 Months – 39 Years · All sexes · Updated Aug 11, 2026 · NCT05057702

Atovaquone Combined With Radiation in Children With Malignant Brain Tumors

RecruitingPhase 1
Ages 2 to 25 · All sexes · Updated Aug 3, 2026 · NCT06624371

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

RecruitingPhase 1/2
Ages 4 to 39 · All sexes · Updated Jul 20, 2026 · NCT05278208

CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal Irradiation

RecruitingObservational study
All ages · All sexes · Updated Jul 6, 2026 · NCT07085325

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.