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Mental Disorders clinical trials recruiting in the U.S.

61 studies for Mental Disorders are recruiting participants at sites across the United States.

Mental disorders (also called mental illnesses) include a wide range of problems. There are many causes. Learn more about what can help.

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Recently updated studies

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Nov 12, 2026 · NCT06887192

Trauma Adapted Yoga for Adolescents and Young Adults in Psychiatric Outpatient Treatment

Recruiting
Ages 12 to 29 · All sexes · Updated Nov 12, 2026 · NCT07934082

Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers

RecruitingHealthy volunteers welcome
Ages 21 to 75 · All sexes · Updated Nov 9, 2026 · NCT06977503

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

RecruitingPhase 2
Ages 8 to 17 · All sexes · Updated Nov 9, 2026 · NCT06595953

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Nov 6, 2026 · NCT01266577

Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa

Recruiting
Ages 18 to 55 · Women · Updated Nov 5, 2026 · NCT07581158

HNC: Human Neural Circuits Electrophysiology During Cognition

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT05962424

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Oct 29, 2026 · NCT06297590

Recovering Sleep After Trauma

Recruiting
Ages 18 to 65 · All sexes · Updated Oct 29, 2026 · NCT07196332

Virtual Reality Viewing of Unaltered Streetscape Versus Digitally Manipulated Opposite Streetscape to Assess Psychosocial Response in Participants

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07216534

Successful Transitions and Reintegration Tools for Veterans (START-VETS)

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT04366531

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Oct 15, 2026 · NCT07459647

Facilitation to Increase Tobacco Treatment

Recruiting
All ages · All sexes · Updated Oct 15, 2026 · NCT07455526

Supporting Treatment Access and Recovery in COD

Recruiting
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05138614

NightWare and Cardiovascular Health in Veterans With PTSD

RecruitingHealthy volunteers welcome
Ages 22 to 88 · All sexes · Updated Oct 8, 2026 · NCT06419959

Efficacy of the I-CARE Digital Health Intervention

Recruiting
Ages 12 to 17 · All sexes · Updated Oct 1, 2026 · NCT07150832

SBIR/ STTR Family Check-up Online

RecruitingHealthy volunteers welcome
All ages · All sexes · Updated Sep 29, 2026 · NCT06876246

Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms

Recruiting
Ages 18 to 64 · All sexes · Updated Sep 29, 2026 · NCT07103902

Engaging Mental Health Services for Preschoolers at Risk

Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07054554

Targeted Plasticity Therapy for PTSD

Recruiting
Ages 22 to 79 · All sexes · Updated Sep 16, 2026 · NCT06266364

GLP-1R Agonist Treatment for Opioid Use Disorder

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 28, 2026 · NCT06548490

Harm Reduction Services

Recruiting
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05776316

Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care

Recruiting
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07549178

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.