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Mental Disorders clinical trials recruiting in the U.S.

63 studies for Mental Disorders are recruiting participants at sites across the United States.

Mental disorders (also called mental illnesses) include a wide range of problems. There are many causes. Learn more about what can help.

Cities with the most studies

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Recently updated studies

SBIR/ STTR Family Check-up Online

RecruitingHealthy volunteers welcome
All ages · All sexes · Updated Sep 29, 2026 · NCT06876246

Successful Transitions and Reintegration Tools for Veterans (START-VETS)

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT04366531

Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms

Recruiting
Ages 18 to 64 · All sexes · Updated Sep 29, 2026 · NCT07103902

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

RecruitingPhase 2
Ages 8 to 17 · All sexes · Updated Sep 28, 2026 · NCT06595953

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 28, 2026 · NCT01266577

NightWare and Cardiovascular Health in Veterans With PTSD

RecruitingHealthy volunteers welcome
Ages 22 to 88 · All sexes · Updated Sep 22, 2026 · NCT06419959

Engaging Mental Health Services for Preschoolers at Risk

Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07054554

Targeted Plasticity Therapy for PTSD

Recruiting
Ages 22 to 79 · All sexes · Updated Sep 16, 2026 · NCT06266364

Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers

RecruitingHealthy volunteers welcome
Ages 21 to 75 · All sexes · Updated Sep 9, 2026 · NCT06977503

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 1, 2026 · NCT07459647

GLP-1R Agonist Treatment for Opioid Use Disorder

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 28, 2026 · NCT06548490

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Aug 27, 2026 · NCT06887192

Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

RecruitingObservational studyHealthy volunteers welcome
30 Days – 99 Years · All sexes · Updated Aug 24, 2026 · NCT01778504

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Aug 24, 2026 · NCT06297590

Harm Reduction Services

Recruiting
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05776316

Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care

Recruiting
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07549178

A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

Recruiting
Ages 13 to 24 · All sexes · Updated Aug 12, 2026 · NCT07348666

Honest, Open, Proud (HOP): A Peer Delivered, Co-occurring Disorders Intervention for Justice-involved Veterans

Recruiting
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT07742722

Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder

RecruitingHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Jul 23, 2026 · NCT06834217

Cognitive Strategies in Early Psychosis 2

RecruitingPhase 3
Ages 18 to 35 · All sexes · Updated Jul 23, 2026 · NCT07263022

Transition Care for FEP

RecruitingObservational study
Ages 18 to 40 · All sexes · Updated Jul 20, 2026 · NCT07713849

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Jul 16, 2026 · NCT06376734

Stimulation-Induced Changes in Fronto-Limbic Network

Recruiting
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT05854160

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.