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Merkel Cell Carcinoma clinical trials recruiting in the U.S.
24 studies for Merkel Cell Carcinoma are recruiting participants at sites across the United States.
Cities with the most studies
- Houston, TX6 studies
- Boston, MA5 studies
- New York City, NY4 studies
- San Antonio, TX4 studies
- Tampa, FL4 studies
- Queens, NY3 studies
- Jacksonville, FL3 studies
- Arlington, VA3 studies
- Seattle, WA3 studies
- Washington, DC3 studies
- Nashville, TN3 studies
- St. Louis, MO3 studies
- Miami, FL3 studies
- Pittsburgh, PA3 studies
- Los Angeles, CA3 studies
By state
- California5 studies
- Florida11 studies
- Maryland3 studies
- Massachusetts5 studies
- Michigan5 studies
- Missouri3 studies
- New Jersey3 studies
- New York4 studies
- North Carolina3 studies
- Pennsylvania4 studies
- Tennessee3 studies
- Texas8 studies
- Virginia3 studies
- Washington4 studies
Recently updated studies
Phase II Study of Peptide Receptor Radionuclide Therapy in Combination With Immunotherapy for Patients With Merkel Cell Cancer
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05583708Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
RecruitingPhase 1
Ages 18 to 100 · All sexes · Updated Sep 22, 2026 · NCT07006727Studies of Dermatologic Diseases Biospecimen Acquisition Protocol
RecruitingObservational studyHealthy volunteers welcome
1 Day – 100 Years · All sexes · Updated Sep 22, 2026 · NCT02471352Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors
RecruitingPhase 1/2
Ages 18 to 99 · All sexes · Updated Sep 22, 2026 · NCT06814496A Study of CRD3874-SI in People With Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06021626Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus
RecruitingPhase 2
All ages · All sexes · Updated Sep 4, 2026 · NCT02479698Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05896839Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
RecruitingPhase 1/2
Ages 16 and older · All sexes · Updated Aug 20, 2026 · NCT05269381A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT05859074A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07749586The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07285044Hypofractionated Radiation Therapy for Merkel Cell Carcinoma
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT05100095Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT04975152MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05076760Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06947928EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers
RecruitingPhase 2
Ages 18 to 99 · All sexes · Updated Mar 10, 2026 · NCT06223659Neoadjuvant PD-1 Blockade in Resectable Merkel Cell Carcinoma
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT05496036TIL Therapy in cSCC and MCC
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT07288073IFx-Hu2.0 As An Adjunctive Therapy To Pembrolizumab In Advanced Or Metastatic Merkel Cell Carcinoma (MCC)
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 15, 2025 · NCT06940440A Beta-only IL-2 ImmunoTherapY Study
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.