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Metabolic Disorders clinical trials recruiting in the U.S.
55 studies for Metabolic Disorders are recruiting participants at sites across the United States.
Your metabolism makes energy from the food you eat. A metabolic disorder disrupts this process. One example is diabetes. Learn more.
Cities with the most studies
- Washington, DC11 studies
- St. Louis, MO8 studies
- Ann Arbor, MI8 studies
- New York City, NY7 studies
- Durham, NC7 studies
- Houston, TX6 studies
- Baltimore, MD6 studies
- Chicago, IL6 studies
- Boston, MA5 studies
- Seattle, WA4 studies
- Los Angeles, CA4 studies
- Philadelphia, PA4 studies
- Miami, FL4 studies
- Nashville, TN4 studies
- Cleveland, OH3 studies
- Birmingham, AL3 studies
- Mountain View, CA3 studies
- Fresno, CA3 studies
- Sacramento, CA3 studies
- Jacksonville, FL3 studies
- Albuquerque, NM3 studies
- Cincinnati, OH3 studies
- Pittsburgh, PA3 studies
- Orlando, FL3 studies
- Simi Valley, CA3 studies
- Hialeah, FL3 studies
- Rochester, MN3 studies
- Escondido, CA3 studies
- San Antonio, TX3 studies
- Aurora, CO3 studies
By state
- Alabama3 studies
- California12 studies
- Colorado6 studies
- Florida7 studies
- Illinois6 studies
- Indiana5 studies
- Louisiana3 studies
- Maryland15 studies
- Massachusetts8 studies
- Michigan10 studies
- Minnesota3 studies
- Missouri8 studies
- New Mexico3 studies
- New York11 studies
- North Carolina9 studies
- Ohio7 studies
- Pennsylvania5 studies
- Tennessee4 studies
- Texas7 studies
- Virginia4 studies
- Washington4 studies
Recently updated studies
Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia
RecruitingObservational studyHealthy volunteers welcome
1 Month – 100 Years · All sexes · Updated Nov 12, 2026 · NCT02890342Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome
RecruitingObservational study
1 Month – 115 Years · All sexes · Updated Nov 9, 2026 · NCT00001456A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Nov 6, 2026 · NCT06525636Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)
RecruitingObservational study
7 Months – 15 Months · All sexes · Updated Nov 5, 2026 · NCT06805695A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07595549Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
RecruitingObservational studyHealthy volunteers welcome
Ages 1 to 100 · All sexes · Updated Nov 4, 2026 · NCT01143454Natural History of the Human Biological Response to Environmental Exposure and Injury
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Oct 29, 2026 · NCT04888923Clinical and Laboratory Study of Methylmalonic Acidemia
RecruitingObservational studyHealthy volunteers welcome
1 Month – 115 Years · All sexes · Updated Oct 29, 2026 · NCT00078078A Natural History Study of Metabolic Sizing in Health and Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 99 · All sexes · Updated Oct 27, 2026 · NCT05398783Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia
RecruitingPhase 3
Ages 12 to 17 · All sexes · Updated Oct 26, 2026 · NCT07473843A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Oct 23, 2026 · NCT06419374A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Oct 23, 2026 · NCT06318169Evaluation of Children With Endocrine and Metabolic-Related Conditions
RecruitingObservational study
3 Months – 100 Years · All sexes · Updated Oct 21, 2026 · NCT02769975Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
RecruitingObservational studyHealthy volunteers welcome
Ages 14 to 18 · All sexes · Updated Oct 15, 2026 · NCT06007404Interactive Roles of Cardiorespiratory Fitness and Adiposity on Glucose and Vascular Control After Physical Inactivity
RecruitingHealthy volunteers welcome
Ages 18 to 40 · All sexes · Updated Oct 9, 2026 · NCT06842225A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07491172Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency
RecruitingObservational study
Ages 2 to 40 · Men · Updated Sep 16, 2026 · NCT05600946Use of Cysteamine in the Treatment of Cystinosis
RecruitingObservational study
1 Week – 115 Years · All sexes · Updated Sep 16, 2026 · NCT00359684Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
RecruitingPhase 1/2
Up to age 20 · All sexes · Updated Sep 16, 2026 · NCT00920972A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Sep 16, 2026 · NCT07723833METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)
RecruitingPhase 2
Ages 18 to 69 · All sexes · Updated Sep 15, 2026 · NCT07699380Improving Coronary Vascular Health in Women
RecruitingPhase 2
Ages 45 to 75 · Women · Updated Sep 8, 2026 · NCT06843902Impact of NMES and HPRO on Recovery After SAH- Pilot Study
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT03201094A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
RecruitingPhase 1/2
Ages 35 to 70 · All sexes · Updated Aug 21, 2026 · NCT06575426A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
RecruitingObservational study
1 Month – 100 Years · All sexes · Updated Aug 19, 2026 · NCT06092346From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.