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Metabolic Disorders clinical trials recruiting in the U.S.
55 studies for Metabolic Disorders are recruiting participants at sites across the United States.
Your metabolism makes energy from the food you eat. A metabolic disorder disrupts this process. One example is diabetes. Learn more.
Cities with the most studies
- Washington, DC11 studies
- Ann Arbor, MI8 studies
- New York City, NY8 studies
- St. Louis, MO7 studies
- Durham, NC7 studies
- Chicago, IL7 studies
- Houston, TX6 studies
- Baltimore, MD6 studies
- Boston, MA5 studies
- Los Angeles, CA5 studies
- Philadelphia, PA4 studies
- Nashville, TN4 studies
- Seattle, WA4 studies
- Aurora, CO4 studies
- Miami, FL4 studies
- Cleveland, OH3 studies
- Portland, OR3 studies
- Birmingham, AL3 studies
- Fort Collins, CO3 studies
- Rochester, MN3 studies
- Mountain View, CA3 studies
- Sacramento, CA3 studies
- Orlando, FL3 studies
- Escondido, CA3 studies
- Fresno, CA3 studies
- Jacksonville, FL3 studies
- Cincinnati, OH3 studies
- Simi Valley, CA3 studies
- Louisville, KY3 studies
- Hialeah, FL3 studies
- Albuquerque, NM3 studies
- San Antonio, TX3 studies
- Town 'n' Country, FL3 studies
- Rochester, NY3 studies
- Pittsburgh, PA3 studies
By state
- Alabama3 studies
- California13 studies
- Colorado8 studies
- Florida7 studies
- Georgia3 studies
- Illinois7 studies
- Indiana5 studies
- Kentucky3 studies
- Louisiana3 studies
- Maryland15 studies
- Massachusetts8 studies
- Michigan10 studies
- Minnesota3 studies
- Missouri7 studies
- New Mexico3 studies
- New York12 studies
- North Carolina9 studies
- Ohio6 studies
- Oregon3 studies
- Pennsylvania5 studies
- Tennessee4 studies
- Texas7 studies
- Virginia4 studies
- Washington4 studies
Recently updated studies
Natural History of the Human Biological Response to Environmental Exposure and Injury
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Sep 28, 2026 · NCT04888923A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia
RecruitingObservational studyHealthy volunteers welcome
1 Month – 100 Years · All sexes · Updated Sep 28, 2026 · NCT02890342Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
RecruitingObservational studyHealthy volunteers welcome
Ages 1 to 100 · All sexes · Updated Sep 22, 2026 · NCT01143454A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT06525636A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Sep 18, 2026 · NCT07491172A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Sep 16, 2026 · NCT07723833Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency
RecruitingObservational study
Ages 2 to 40 · Men · Updated Sep 16, 2026 · NCT05600946Use of Cysteamine in the Treatment of Cystinosis
RecruitingObservational study
1 Week – 115 Years · All sexes · Updated Sep 16, 2026 · NCT00359684Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
RecruitingPhase 1/2
Up to age 20 · All sexes · Updated Sep 16, 2026 · NCT00920972METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)
RecruitingPhase 2
Ages 18 to 69 · All sexes · Updated Sep 15, 2026 · NCT07699380A Natural History Study of Metabolic Sizing in Health and Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 2 to 99 · All sexes · Updated Sep 15, 2026 · NCT05398783Clinical and Laboratory Study of Methylmalonic Acidemia
RecruitingObservational studyHealthy volunteers welcome
1 Month – 115 Years · All sexes · Updated Sep 10, 2026 · NCT00078078Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome
RecruitingObservational study
1 Month – 115 Years · All sexes · Updated Sep 9, 2026 · NCT00001456Improving Coronary Vascular Health in Women
RecruitingPhase 2
Ages 45 to 75 · Women · Updated Sep 8, 2026 · NCT06843902Impact of NMES and HPRO on Recovery After SAH- Pilot Study
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT03201094A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Sep 3, 2026 · NCT06318169A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 3, 2026 · NCT06419374Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)
RecruitingObservational study
7 Months – 15 Months · All sexes · Updated Aug 31, 2026 · NCT06805695A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
RecruitingPhase 1/2
Ages 35 to 70 · All sexes · Updated Aug 21, 2026 · NCT06575426A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
RecruitingObservational study
1 Month – 100 Years · All sexes · Updated Aug 19, 2026 · NCT06092346Evaluation of Children With Endocrine and Metabolic-Related Conditions
RecruitingObservational study
3 Months – 100 Years · All sexes · Updated Aug 13, 2026 · NCT02769975Blood Specimen Collection For Laboratory Assay Research
RecruitingObservational studyMentions payment for participants
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT06046651An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency
RecruitingPhase 3
24 Hours – 7 Months · Men · Updated Aug 12, 2026 · NCT06255782NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals
RecruitingPhase 2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT04055428From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.