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Mitral Valve Insufficiency clinical trials recruiting in the U.S.
26 studies for Mitral Valve Insufficiency are recruiting participants at sites across the United States.
Cities with the most studies
- New York City, NY13 studies
- Los Angeles, CA9 studies
- Nashville, TN8 studies
- Houston, TX8 studies
- Atlanta, GA8 studies
- Portland, OR8 studies
- Cleveland, OH8 studies
- The Bronx, NY7 studies
- Phoenix, AZ7 studies
- Minneapolis, MN6 studies
- Boston, MA6 studies
- Thousand Oaks, CA6 studies
- Newark, NJ6 studies
- Tucson, AZ5 studies
- San Francisco, CA5 studies
- Cincinnati, OH4 studies
- Pittsburgh, PA4 studies
- Chicago, IL4 studies
- Ann Arbor, MI4 studies
- Seattle, WA4 studies
- West Jordan, UT3 studies
- San Antonio, TX3 studies
- Indianapolis, IN3 studies
- San Diego, CA3 studies
- Wichita, KS3 studies
- Charlotte, NC3 studies
- Norfolk, VA3 studies
- New Rochelle, NY3 studies
- Harrisburg, PA3 studies
- Detroit, MI3 studies
- Columbus, OH3 studies
- Rochester, MN3 studies
- Philadelphia, PA3 studies
- Oklahoma City, OK3 studies
- Baltimore, MD3 studies
- St. Louis, MO3 studies
- Tampa, FL3 studies
By state
- Arizona9 studies
- California13 studies
- Florida5 studies
- Georgia8 studies
- Illinois5 studies
- Indiana3 studies
- Kansas4 studies
- Maryland3 studies
- Massachusetts6 studies
- Michigan4 studies
- Minnesota9 studies
- Missouri4 studies
- New Jersey6 studies
- New York17 studies
- North Carolina3 studies
- Ohio11 studies
- Oklahoma5 studies
- Oregon8 studies
- Pennsylvania6 studies
- Tennessee8 studies
- Texas9 studies
- Utah3 studies
- Virginia5 studies
- Washington4 studies
Recently updated studies
TransCatheter Replacement Of the Mitral Valve With the Novel Cephea Mitral Valve System
Recruiting
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07798726Early Feasibility Study of the Capstan Medical TMVR System
Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07917208Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT03242642TVMR With the INNOVALVE System Trial - Early Feasibility Study
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT04919980Cephea Early Feasibility Study
Recruiting
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05061004Abbott Cephea Mitral Valve Disease Registry
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07069673Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06077201EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States)
Recruiting
Ages 21 and older · All sexes · Updated Sep 1, 2026 · NCT07517588Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07130994ATLAS (AltaValve) Pivotal Trial
Recruiting
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06465745The CardioClip Study
Recruiting
Ages 18 to 90 · All sexes · Updated Jun 29, 2026 · NCT06241430STS/ACC TVT Registry Mitral Module
RecruitingObservational studyHealthy volunteers welcome
Ages 1 and older · All sexes · Updated Jun 15, 2026 · NCT02245763CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry
RecruitingObservational study
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT04688190Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock
Recruiting
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT05298124A Clinical Study of GeminiOne TEER System for the Treatment of Severe, Symptomatic MR.
Recruiting
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT07086534DELINEATE-Prospective
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07197736The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Mosaic Mitral Valve: Long-Term Outcomes in Patients Under 65
RecruitingObservational study
Ages 18 to 65 · All sexes · Updated Feb 20, 2026 · NCT06917586The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).
Recruiting
Ages 18 and older · All sexes · Updated Jan 13, 2026 · NCT04408430AMEND TS Early Feasibility Study
Recruiting
Ages 21 and older · All sexes · Updated Jan 7, 2026 · NCT06951672Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease
RecruitingObservational study
Ages 18 to 90 · All sexes · Updated Jan 2, 2026 · NCT06780241Use of Phenylephrine for Assessment of Mitral Regurgitation Severity
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 20, 2025 · NCT04500899Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 6, 2025 · NCT06911099An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System
Recruiting
Ages 18 and older · All sexes · Updated Mar 17, 2025 · NCT04029337Assessing the Relationship Between Symptoms and Mitral Regurgitnant. Severity
RecruitingObservational study
Ages 18 and older · Men · Updated Dec 17, 2024 · NCT06738615From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.