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Myelodysplastic Syndromes clinical trials in Massachusetts

22 studies for Myelodysplastic Syndromes are looking for participants at sites in Massachusetts.

Cities in Massachusetts

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06484062

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

  • Tufts Medical Center, Boston
  • Beth Israel Deaconess Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
  • and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT03471260

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

  • Massachusetts General Hospital, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06465953

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

  • Brigham and Women's Hospital, Boston
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Jul 28, 2026 · NCT07020533

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

  • Dana-Farber Cancer Institute, Boston
  • Brigham and Women's Hospital, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06138587

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

  • Boston Children's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 12 and older · All sexes · Updated Jun 17, 2026 · NCT04024761

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

  • Dana-Farber Cancer Institute, Boston
  • Dana Farber Cancer Institute at St. Elizabeth's, Brighton
  • Dana Farber Cancer Institute at Merrimack Valley, Methuen
  • and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT02269592

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT04256317

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

  • Massachusetts General Hospital, Boston
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Venetoclax Basket Trial for High Risk Hematologic Malignancies

  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 1 to 40 · All sexes · Updated Mar 12, 2026 · NCT05292664

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

  • DFCI/BWH Brigham and Women's Hospital, Boston
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Mar 10, 2026 · NCT06059391

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Worcester
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

IS-free Treg HaploHCT

  • Dana Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Oct 20, 2025 · NCT04678401

HEME Home Transfusion Program

  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2025 · NCT06487247

Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform

  • Shwachman-Diamond Syndrome Alliance Inc., Woburn
RecruitingObservational study
All ages · All sexes · Updated May 31, 2025 · NCT06999954

Study of REM-422 in Patients With AML or Higher Risk MDS

  • Massachusetts General Hospital, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 23, 2025 · NCT06297941

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 15, 2025 · NCT06462365

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.