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Myelodysplastic Syndromes clinical trials in Ohio

22 studies for Myelodysplastic Syndromes are looking for participants at sites in Ohio.

Cities in Ohio

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

  • Case Western Reserve University, Cleveland
  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

  • Cleveland Clinic, Cleveland
  • The Ohio State University, Columbus
  • Taylor Cancer Research Center, Maumee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05320198

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06577441

Collection of Tissue Samples for Cancer Research

  • Ohio State University, Columbus
RecruitingObservational study
2 Months · All sexes · Updated Sep 16, 2026 · NCT00900198

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

  • Case Comprehensive Cancer Center, University Hospitals Cleveland Medical Center Seidman Cancer Center, Cleveland
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06904482

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

  • Ohio State University, The James Comprehensive Cancer, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06846606

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

  • Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT03471260

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06465953

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

  • Children's Hospital Medical Center of Akron, Akron
  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Rainbow Babies and Childrens Hospital, Cleveland
  • and 3 more
RecruitingPhase 1/2
Up to age 22 · All sexes · Updated Aug 25, 2026 · NCT04726241

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

  • Gabrail Cancer Center Research, Canton
  • Cleveland Clinic - Cleveland, Cleveland
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06499285

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

  • Cleveland Clinic, Cleveland
  • The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT05308264

A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome

  • GSK Investigational Site, Canton
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06847867

5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies

  • Cleveland Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT04187703

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

  • Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT04256317

Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

  • Ohio State University Medical Center, Columbus
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Mar 25, 2026 · NCT03533816

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

  • The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

  • Cleveland Clinic Cancer Center, Cleveland
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06543381

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy

  • Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingPhase 2
3 Months · All sexes · Updated Nov 12, 2025 · NCT02143830

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Cincinnati
  • Massive Bio SYNERGY-AI site, Columbus
  • Massive Bio SYNERGY-AI site, Mayfield Heights
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

  • The Ohio State University Wexner Medical Center - James Cancer Hosp, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT06501196

HPC Offered for PRESERVE Expansion

  • The Ohio State University Medical Center, Columbus
RecruitingObservational study
Ages 12 to 80 · All sexes · Updated Aug 28, 2025 · NCT07145411

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.