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Myeloproliferative Neoplasms clinical trials recruiting in the U.S.

51 studies for Myeloproliferative Neoplasms are recruiting participants at sites across the United States.

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Recently updated studies

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07441694

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

RecruitingPhase 2
Ages 12 and older · All sexes · Updated Nov 10, 2026 · NCT03589729

Asciminib Roll-over Study

RecruitingPhase 4
Ages 7 to 100 · All sexes · Updated Nov 9, 2026 · NCT04877522

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 29, 2026 · NCT06265584

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07469891

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

RecruitingObservational study
Ages 0 to 38 · All sexes · Updated Oct 29, 2026 · NCT06131801

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 28, 2026 · NCT01137643

A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT06661915

A Study to Evaluate DMR-001 in Participants With CALR-mutant Myeloproliferative Neoplasms

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT07849231

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Oct 23, 2026 · NCT06059391

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT05320198

Therapeutic RSK1 Targeting in Myeloid Malignancies

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT07379125

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT05423691

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

Recruiting
Up to age 30 · All sexes · Updated Oct 20, 2026 · NCT06421155

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

Recruiting
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT05745285

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated Oct 9, 2026 · NCT06315309

Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04282187

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.