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Neurofibromatosis clinical trials recruiting in the U.S.

7 studies for Neurofibromatosis are recruiting participants at sites across the United States.

Neurofibromatosis (NF) is a genetic disorder that causes tumors to grow on nerves. Learn about the types, their symptoms, and how they are treated.

Recently updated studies

PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT06961565

The NF Registry Sponsored by the Children's Tumor Foundation

RecruitingObservational study
All ages · All sexes · Updated Oct 22, 2026 · NCT01885767

Natural History Study of Patients With Neurofibromatosis Type 2

RecruitingObservational study
Ages 8 to 75 · All sexes · Updated Oct 16, 2026 · NCT00598351

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05489783

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT07102394

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT07237100

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.