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Neurofibromatosis clinical trials recruiting in the U.S.

7 studies for Neurofibromatosis are recruiting participants at sites across the United States.

Neurofibromatosis (NF) is a genetic disorder that causes tumors to grow on nerves. Learn about the types, their symptoms, and how they are treated.

Recently updated studies

Natural History Study of Patients With Neurofibromatosis Type 2

RecruitingObservational study
Ages 8 to 75 · All sexes · Updated Sep 1, 2026 · NCT00598351

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05489783

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT07102394

PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Dec 4, 2025 · NCT06961565

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT07237100

Neurofibromatosis (NF) Registry Portal

RecruitingObservational study
All ages · All sexes · Updated Aug 30, 2023 · NCT01885767

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.