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Neurofibrosarcoma clinical trials recruiting in the U.S.

14 studies for Neurofibrosarcoma are recruiting participants at sites across the United States.

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Recently updated studies

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

RecruitingPhase 1
Ages 12 to 120 · All sexes · Updated Sep 23, 2026 · NCT04222413

DoD Award NF230020 Identification of Metabolic Markers and Statistical Prediction of MPNST for Rapid Diagnosis and Assessment of Surgical Margins

RecruitingObservational study
Ages 1 and older · All sexes · Updated Sep 18, 2026 · NCT07298083

Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05732831

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05245500

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

RecruitingObservational study
Ages 3 to 120 · All sexes · Updated Sep 2, 2026 · NCT06222203

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

RecruitingPhase 2
Ages 18 to 99 · All sexes · Updated Aug 24, 2026 · NCT05253131

Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor

RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Aug 11, 2026 · NCT07549022

SPEARHEAD-3 Pediatric Study

RecruitingPhase 1/2
Ages 2 to 21 · All sexes · Updated Aug 11, 2026 · NCT05642455

Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06735820

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

RecruitingPhase 1
Up to age 21 · All sexes · Updated May 19, 2026 · NCT04897321

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

RecruitingPhase 2
12 Months · All sexes · Updated May 6, 2026 · NCT05985161

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

RecruitingObservational study
All ages · All sexes · Updated Mar 9, 2026 · NCT03141021

A Study of ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST)

RecruitingPhase 2
Ages 16 and older · All sexes · Updated Feb 5, 2026 · NCT04872543

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.