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Neuromyelitis Optica clinical trials recruiting in the U.S.
14 studies for Neuromyelitis Optica are recruiting participants at sites across the United States.
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Recently updated studies
A Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)
RecruitingPhase 3
Ages 2 to 11 · All sexes · Updated Oct 1, 2026 · NCT05199688A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06680037Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During Pregnancy
RecruitingObservational study
Ages 15 and older · Women · Updated Aug 31, 2026 · NCT05909761Stem Cell Ophthalmology Treatment Study II
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT03011541Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT05966467Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT05982925Study of Ultomiris® (Ravulizumab) Safety in Pregnancy
RecruitingObservational study
All ages · Women · Updated Apr 16, 2026 · NCT06312644Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder
RecruitingPhase 2
Ages 2 to 17 · All sexes · Updated Dec 5, 2025 · NCT05549258Efgartigimod for the Treatment of Acute Optic Neuritis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT06453694Study of the Clinical and Radiological Impact of Ravulizumab in People With Neuromyelitis Optica Spectrum Disorder
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 5, 2025 · NCT06398158Biorepository and Registry for Plasma Exchange Patients
RecruitingObservational study
Ages 12 to 99 · All sexes · Updated May 20, 2025 · NCT05004493Impact of a Structured Wellness Behavioral Intervention on Quality of Life in NMOSD
Recruiting
Ages 18 and older · All sexes · Updated Apr 17, 2025 · NCT06780709Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD
Recruiting
Ages 18 and older · All sexes · Updated Apr 10, 2025 · NCT05566769MS-ResearchBiomarkerS
RecruitingObservational studyHealthy volunteers welcomeMentions payment for participants
Ages 18 and older · All sexes · Updated Feb 6, 2024 · NCT05204459From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.