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Osteoporosis clinical trials recruiting in the U.S.
18 studies for Osteoporosis are recruiting participants at sites across the United States.
Osteoporosis is a disease that weakens your bones and makes them more likely to break or fracture. There are no symptoms until the first bone break.
Cities with the most studies
By state
- Colorado3 studies
- Maryland4 studies
- Massachusetts3 studies
- North Carolina3 studies
- Pennsylvania3 studies
Recently updated studies
A Natural History Study of Bone and Mineral Disorders
RecruitingObservational study
1 Day โ 100 Years ยท All sexes ยท Updated Sep 28, 2026 ยท NCT00024804Preserving Geriatric Muscle With an Osteoporosis Medication
RecruitingPhase 4
Ages 65 and older ยท All sexes ยท Updated Sep 23, 2026 ยท NCT06118905Effect of Acetylcholinesterase Inhibitors on Bone Metabolism
RecruitingPhase 2
Ages 50 and older ยท All sexes ยท Updated Sep 21, 2026 ยท NCT06041789GLP-1R Actions on Muscle and the Skeleton
RecruitingPhase 4
Ages 18 to 50 ยท All sexes ยท Updated Aug 27, 2026 ยท NCT07154719Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females
RecruitingPhase 1Healthy volunteers welcome
Ages 45 to 70 ยท Women ยท Updated Jul 23, 2026 ยท NCT07365514U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures
Recruiting
Ages 22 and older ยท All sexes ยท Updated Jul 20, 2026 ยท NCT07325578Bone, Exercise, Alendronate, and Caloric Restriction
RecruitingPhase 4
Ages 60 and older ยท All sexes ยท Updated Jun 9, 2026 ยท NCT05764733Mode of Exercise and Bone Biomarkers in Older Veterans
RecruitingHealthy volunteers welcome
Ages 60 and older ยท All sexes ยท Updated May 22, 2026 ยท NCT05266976The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures
RecruitingObservational study
Ages 50 and older ยท All sexes ยท Updated May 13, 2026 ยท NCT07027306Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 ยท All sexes ยท Updated May 7, 2026 ยท NCT07083557RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE
Recruiting
Ages 50 and older ยท All sexes ยท Updated May 5, 2026 ยท NCT06455085Combined Anabolic Therapy
RecruitingPhase 4Healthy volunteers welcome
Ages 45 and older ยท Women ยท Updated Apr 17, 2026 ยท NCT06558188Synbiotic to Attenuate Resorption of the Skeleton
RecruitingHealthy volunteers welcome
Ages 60 and older ยท Women ยท Updated Mar 17, 2026 ยท NCT06389539Prunes Preventing Bone Loss in Perimenopause
RecruitingHealthy volunteers welcome
Ages 44 to 55 ยท Women ยท Updated Feb 4, 2026 ยท NCT07120997OsteoPorotic fracTure preventION System (OPTIONS) Research Study
Recruiting
Ages 65 and older ยท All sexes ยท Updated Jan 29, 2026 ยท NCT06731608Estrogen Supplementation and Bone Health in Women With CF
RecruitingPhase 4
Ages 0 to 100 ยท Women ยท Updated Nov 14, 2025 ยท NCT05704036Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty
RecruitingHealthy volunteers welcome
Ages 50 and older ยท All sexes ยท Updated Oct 14, 2025 ยท NCT05845021Genetic Regulators of Bone Health That Are Unique to Vertebral Bone
RecruitingObservational study
Ages 18 to 85 ยท All sexes ยท Updated Apr 3, 2024 ยท NCT05946278From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.