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Plexiform Neurofibroma clinical trials recruiting in the U.S.

8 studies for Plexiform Neurofibroma are recruiting participants at sites across the United States.

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Recently updated studies

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

RecruitingObservational studyHealthy volunteers welcome
Ages 5 and older · All sexes · Updated Sep 22, 2026 · NCT02544022

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

RecruitingObservational study
Ages 3 to 120 · All sexes · Updated Sep 2, 2026 · NCT06222203

Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas

RecruitingPhase 1
Ages 16 and older · All sexes · Updated Aug 24, 2026 · NCT06502171

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

RecruitingPhase 2
Ages 12 and older · All sexes · Updated Jul 29, 2026 · NCT06541847

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

RecruitingPhase 2
Ages 1 to 8 · All sexes · Updated May 29, 2026 · NCT06188741

PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Dec 4, 2025 · NCT06961565

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.