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Postpartum Depression clinical trials recruiting in the U.S.
30 studies for Postpartum Depression are recruiting participants at sites across the United States.
Postpartum (post-pregnancy) depression can begin anytime within the first year after childbirth. Learn about the symptoms of postpartum depression.
Cities with the most studies
By state
- Colorado4 studies
- Illinois3 studies
- Massachusetts3 studies
- New York5 studies
- Ohio3 studies
- South Carolina3 studies
- Utah3 studies
Recently updated studies
Maternal Stress on Human Milk and Infant Outcomes
Recruiting
Ages 18 to 50 · Women · Updated Nov 10, 2026 · NCT04821544Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT06767566Restoring Emotional Needs With Exogenous Ketones for Women With Postpartum Depression
RecruitingHealthy volunteers welcome
Ages 18 to 45 · Women · Updated Nov 5, 2026 · NCT07919392The Goal is to Examine the Impact of Doula-delivered, Nurse-coordinated Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission.
Recruiting
Ages 18 and older · Women · Updated Oct 23, 2026 · NCT07787845Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
Recruiting
Ages 18 and older · Women · Updated Oct 13, 2026 · NCT07485036Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
Recruiting
Ages 15 to 49 · Women · Updated Sep 28, 2026 · NCT07799805SAINT in Postpartum Depression (PPD)
Recruiting
Ages 18 to 45 · Women · Updated Sep 28, 2026 · NCT07210255Accelerated TMS for Perinatal Depression
Recruiting
Ages 18 to 55 · Women · Updated Sep 18, 2026 · NCT06968390Brexanolone Lifting Outcomes Of Moms
RecruitingPhase 3
Ages 15 to 45 · Women · Updated Sep 16, 2026 · NCT07822321A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone
RecruitingObservational study
Ages 18 and older · Women · Updated Sep 8, 2026 · NCT07398469OBWELL: Innovative Psychotherapeutic Intervention to Treat Postpartum Depression
Recruiting
Ages 18 and older · Women · Updated Sep 8, 2026 · NCT06991166Engage & Connect: A Psychotherapy for Postpartum Depression
Recruiting
All ages · Women · Updated Aug 20, 2026 · NCT05585164Understanding the Role of Doulas in Supporting People With PMADs
RecruitingHealthy volunteers welcome
Ages 18 and older · Women · Updated Aug 14, 2026 · NCT05763537Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression
Recruiting
Ages 18 and older · Women · Updated Aug 14, 2026 · NCT07766161Parents and Babies Pilot
Recruiting
Ages 18 and older · Women · Updated Aug 6, 2026 · NCT07607613Implementation of a Clinical Decision Support Tool for Postpartum Depression
RecruitingHealthy volunteers welcome
Ages 18 and older · Women · Updated Jul 30, 2026 · NCT06818734NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)
RecruitingHealthy volunteers welcome
Ages 18 and older · Women · Updated Jun 17, 2026 · NCT07214597Accelerated iTBS for Post Partum Depression
Recruiting
Ages 18 to 50 · Women · Updated May 22, 2026 · NCT03417960The ROSE Scale-up Study: Informing a Decision About ROSE as Universal PPD Prevention
RecruitingHealthy volunteers welcome
Ages 18 and older · Women · Updated May 18, 2026 · NCT05700760The Mom and Infant Outcomes (MOMI) Study
Recruiting
All ages · Women · Updated May 14, 2026 · NCT06277661ROSE in Sunset Park
RecruitingHealthy volunteers welcome
Ages 18 to 100 · Women · Updated Mar 30, 2026 · NCT04940585Clinical Validation of a Predictive Test for Postpartum Depression
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · Women · Updated Dec 3, 2025 · NCT06831968A Study of a Test for Postpartum Depression at Home
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · Women · Updated Nov 28, 2025 · NCT07186309Postpartum Care in the NICU (PeliCaN) Transitions
Recruiting
Ages 16 and older · Women · Updated Oct 14, 2025 · NCT06521398HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis
Recruiting
Ages 18 and older · All sexes · Updated Jul 20, 2025 · NCT06175104From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.