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Postural Orthostatic Tachycardia Syndrome clinical trials recruiting in the U.S.
14 studies for Postural Orthostatic Tachycardia Syndrome are recruiting participants at sites across the United States.
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Recently updated studies
Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?
RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 21 · Women · Updated Sep 29, 2026 · NCT06616363Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT00921986Inappropriate Sinus Tachycardia Registry
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Aug 27, 2026 · NCT05107635Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07143669Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)
RecruitingObservational studyHealthy volunteers welcome
Ages 14 and older · All sexes · Updated Jul 17, 2026 · NCT06292104Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
RecruitingHealthy volunteers welcome
Ages 12 to 21 · Women · Updated Apr 21, 2026 · NCT05618054Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease
Recruiting
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT07478172A Study of Pyridostigmine in Postural Tachycardia Syndrome
RecruitingPhase 2
Ages 15 to 55 · All sexes · Updated Mar 5, 2026 · NCT00409435Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome
Recruiting
Ages 10 to 18 · All sexes · Updated Feb 13, 2026 · NCT05212129Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Jan 22, 2026 · NCT04806620Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT07189936Restoring Iron Deficiency in POTS
RecruitingPhase 2
Ages 18 to 45 · Women · Updated Dec 11, 2025 · NCT07197905Splanchnic Venous Capacitance in Postural Tachycardia Syndrome
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Dec 5, 2025 · NCT05375968The Long COVID-19 Wearable Device Study
Recruiting
Ages 18 and older · All sexes · Updated May 11, 2025 · NCT05741112From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.