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Postural Orthostatic Tachycardia Syndrome clinical trials recruiting in the U.S.

14 studies for Postural Orthostatic Tachycardia Syndrome are recruiting participants at sites across the United States.

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Recently updated studies

Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?

RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 21 · Women · Updated Sep 29, 2026 · NCT06616363

Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT00921986

Inappropriate Sinus Tachycardia Registry

RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Aug 27, 2026 · NCT05107635

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07143669

Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)

RecruitingObservational studyHealthy volunteers welcome
Ages 14 and older · All sexes · Updated Jul 17, 2026 · NCT06292104

Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?

RecruitingHealthy volunteers welcome
Ages 12 to 21 · Women · Updated Apr 21, 2026 · NCT05618054

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease

Recruiting
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT07478172

A Study of Pyridostigmine in Postural Tachycardia Syndrome

RecruitingPhase 2
Ages 15 to 55 · All sexes · Updated Mar 5, 2026 · NCT00409435

Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome

Recruiting
Ages 10 to 18 · All sexes · Updated Feb 13, 2026 · NCT05212129

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Jan 22, 2026 · NCT04806620

Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT07189936

Restoring Iron Deficiency in POTS

RecruitingPhase 2
Ages 18 to 45 · Women · Updated Dec 11, 2025 · NCT07197905

Splanchnic Venous Capacitance in Postural Tachycardia Syndrome

RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Dec 5, 2025 · NCT05375968

The Long COVID-19 Wearable Device Study

Recruiting
Ages 18 and older · All sexes · Updated May 11, 2025 · NCT05741112

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.