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Premenstrual Syndrome clinical trials recruiting in the U.S.

5 studies for Premenstrual Syndrome are recruiting participants at sites across the United States.

For some women, premenstrual syndrome (PMS) may be so severe it can interfere with normal activities. Find out what you can do to lessen symptoms.

Recently updated studies

CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · Women · Updated Jul 1, 2026 · NCT07679074

Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder

RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 50 · Women · Updated May 7, 2026 · NCT06704594

Identification and Validation of Epigenetic Biomarkers of PMDD

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 50 · Women · Updated May 7, 2026 · NCT06771583

Moderate Aerobic Exercise for Managing Menstrual Cycle Symptoms

Recruiting
Ages 18 to 40 · Women · Updated Jul 24, 2025 · NCT07084714

From ClinicalTrials.gov, data retrieved Oct 3, 2026. Each study sets its own eligibility; the study team decides who can join.