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Propionic Acidemia clinical trials recruiting in the U.S.
6 studies for Propionic Acidemia are recruiting participants at sites across the United States.
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Recently updated studies
Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia
RecruitingObservational studyHealthy volunteers welcome
1 Month – 100 Years · All sexes · Updated Sep 28, 2026 · NCT02890342AAVrh10-PCCA Gene Therapy for Propionic Acidemia
RecruitingPhase 1
6 Months – 2 Years · All sexes · Updated Aug 21, 2026 · NCT07643844A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study
RecruitingPhase 1/2
Ages 1 and older · All sexes · Updated Mar 23, 2026 · NCT05130437A Retrospective Study to Characterize Participants With Propionic Acidemia
RecruitingObservational study
Ages 2 and older · All sexes · Updated Feb 5, 2026 · NCT05769621Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia
RecruitingPhase 1/2
All ages · All sexes · Updated Jan 22, 2026 · NCT04159103An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics
RecruitingObservational study
All ages · All sexes · Updated Apr 15, 2025 · NCT05040178From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.